Evidence map›Paper›PMID 40134287›Full record

Observational studyActa orthopaedica2025

Antibiotic prophylaxis and incidence of infection following elbow arthroplasty: a nationwide study.

Johan E Wänström, Anne Dettmer, Hanna C Björnsson Hallgren, Björn Salomonsson, Oskar Ljungquist, Lars E Adolfsson

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Acta orthopaedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johan E WänströmDepartment of Orthopaedic Surgery, Helsingborg Hospital, Helsingborg; Division of Orthopaedic Surgery Department of Biomedical and Clinical Sciences Linköping University, Linköping, Sweden. johan.e.wanstrom@gmail.com.ORCID 0009-0002-4215-3884
Anne DettmerDivision of Orthopaedic Surgery Department of Biomedical and Clinical Sciences Linköping University, Linköping; Department of Orthopaedic Surgery, Ryhov Hospital, Jönköping, Sweden.
Hanna C Björnsson HallgrenDivision of Orthopaedic Surgery Department of Biomedical and Clinical Sciences Linköping University, Linköping, Sweden.ORCID 0000-0003-2193-1165
Björn SalomonssonDepartment of Clinical Sciences, Karolinska Institutet Danderyd Hospital, Stockholm, Sweden.ORCID 0000-0002-3437-7290
Oskar LjungquistDepartment of Clinical Sciences, Lund University Helsingborg Hospital, Helsingborg, Sweden.
Lars E AdolfssonDivision of Orthopaedic Surgery Department of Biomedical and Clinical Sciences Linköping University, Linköping; Department of Orthopaedics, Faculty of Medicine and Health, Örebro University, Sweden.ORCID 0000-0001-7873-3093

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePeriprosthetic joint infection (PJI) after elbow arthroplasty is a serious complication. Evidence of the best antibiotic prophylaxis for elbow arthroplasty is lacking. We aimed to investigate the regimens presently used in Sweden, incidence of PJI, and the bacteria most frequently found in elbow PJI.

methodsA questionnaire was sent out to all Swedish units performing elbow arthroplasty in 2019 asking about antibiotic prophylaxis routines. The Swedish Elbow Arthroplasty Register (SEAR) and national inpatient and outpatient registers (NPR) from the National Board of Health and Welfare were searched for procedures related to all primary total- or hemi-elbow arthroplasties performed during 2019-2021. Results of microbiological analyses of the suspected PJI cases were collected from the respective laboratory.

resultsMost centers used only cloxacillin (44%) or cloxacillin together with benzylpenicillin (44%), as prophylaxis. 250 primary procedures were performed between 2019 and 2021, and the most used antibiotic prophylaxes were cloxacillin (61%) and cloxacillin with benzylpenicillin (23%). In the NPR, 20 patients (8%) with a diagnosis that could indicate PJI were found and 9 (3.6%) had a confirmed PJI. The most common bacteria were Staphylococcus epidermidis, Cutibacterium acnes, and Staphylococcus aureus.

conclusionMost centers used cloxacillin antibiotic prophylaxis for elbow arthroplasty. The incidence of PJI was 3.6%. The most frequent diagnosed pathogen was Staphylococcus epidermidis.

Indexed as

Anti-Bacterial AgentsAntibiotic ProphylaxisArthroplasty, Replacement, ElbowElbow ProsthesisGram-Positive Bacterial InfectionsProsthesis-Related InfectionsAgedCloxacillinFemaleHumansIncidenceMaleMiddle AgedPenicillin GPropionibacteriaceaeRegistriesAnti-Bacterial AgentsCloxacillinPenicillin G

Identifiers

PMID40134287
PMCPMC11933823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.