Evidence map›Paper›PMID 40134285›Full record

ArticleDiagnostic and interventional radiology (Ankara, Turkey)2025

Evaluating artificial intelligence for a focal nodular hyperplasia diagnosis using magnetic resonance imaging: preliminary findings.

Mecit Kantarcı, Volkan Kızılgöz, Ramazan Terzi, Ahmet Enes Kılıç, Halime Kabalcı, Önder Durmaz, Nil Tokgöz, Mustafa Harman, Ayşegül Sağır Kahraman, Ali Avanaz and 4 more

Abstract read
In one paragraph

Article in Diagnostic and interventional radiology (Ankara, Turkey), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mecit KantarcıErzincan Binali Yıldırım University Faculty of Medicine, Department of Radiology, Erzincan, Türkiye.ORCID 0000-0002-1043-6719
Volkan KızılgözErzincan Binali Yıldırım University Faculty of Medicine, Department of Radiology, Erzincan, Türkiye.ORCID 0000-0003-3450-711X
Ramazan TerziDigital Transformation Office, Presidency of the Republic of Türkiye, Ankara, Türkiye.ORCID 0000-0003-2345-8666
Ahmet Enes KılıçDigital Transformation Office, Presidency of the Republic of Türkiye, Ankara, Türkiye.ORCID 0009-0004-9358-8743
Halime KabalcıErzincan Binali Yıldırım University Faculty of Medicine, Department of Anatomy, Erzincan, Türkiye.ORCID 0009-0009-2027-1653
Önder DurmazErzincan Binali Yıldırım University Faculty of Medicine, Department of Radiology, Erzincan, Türkiye.ORCID 0000-0003-1157-2787
Nil TokgözGazi University Faculty of Medicine, Department of Radiology, Ankara, Türkiye.ORCID 0000-0003-2812-1528
Mustafa HarmanEge University Faculty of Medicine, Department of Radiology, İzmir, Türkiye.ORCID 0000-0001-9234-887X
Ayşegül Sağır Kahramanİnönü University Faculty of Medicine, Department of Radiology, Malatya, Türkiye.ORCID 0000-0002-2147-1181
Ali AvanazAkdeniz University Faculty of Medicine, Department of General Surgery, Antalya, Türkiye.ORCID 0000-0002-4559-4258
Sonay AydınErzincan Binali Yıldırım University Faculty of Medicine, Department of Radiology, Erzincan, Türkiye.ORCID 0000-0002-3812-6333
Gülsüm Özlem ElpekAkdeniz University Faculty of Medicine, Department of Pathology, Antalya, Türkiye.ORCID 0000-0002-1237-5454
Merve YazolGazi University Faculty of Medicine, Department of Radiology, Ankara, Türkiye.ORCID 0000-0003-1437-8998
Bülent AydınlıAkdeniz University Faculty of Medicine, Department of General Surgery, Antalya, Türkiye.ORCID 0000-0002-2242-1012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the effectiveness of artificial intelligence (AI) in diagnosing focal nodular hyperplasia (FNH) of the liver using magnetic resonance imaging (MRI) and compare its performance with that of radiologists.

methodsIn the first phase of the study, the MRIs of 60 patients (30 patients with FNH and 30 patients with no lesions or lesions other than FNH) were processed using a segmentation program and introduced to an AI model. After the learning process, the MRIs of 42 different patients that the AI model had no experience with were introduced to the system. In addition, a radiology resident and a radiology specialist evaluated patients with the same MR sequences. The sensitivity and specificity values were obtained from all three reviews.

resultsThe sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the AI model were found to be 0.769, 0.966, 0.909, and 0.903, respectively. The sensitivity and specificity values were higher than those of the radiology resident and lower than those of the radiology specialist. The results of the specialist versus the AI model revealed a good agreement level, with a kappa (κ) value of 0.777.

conclusionFor the diagnosis of FNH, the sensitivity, specificity, PPV, and NPV of the AI device were higher than those of the radiology resident and lower than those of the radiology specialist. With additional studies focused on different specific lesions of the liver, AI models are expected to be able to diagnose each liver lesion with high accuracy in the future. CLINICAL SIGNIFICANCE: AI is studied to provide assisted or automated interpretation of radiological images with an accurate and reproducible imaging diagnosis.

Indexed as

Artificial IntelligenceFocal Nodular HyperplasiaMagnetic Resonance ImagingAdultAgedFemaleHumansImage Interpretation, Computer-AssistedLiverMaleMiddle AgedPredictive Value of TestsSensitivity and SpecificityYoung AdultArtificial intelligencedeep learningfocal nodular hyperplasialiver lesionmagnetic resonance imaging

Identifiers

PMID40134285
PMCPMC12417915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.