Evidence map›Paper›PMID 40134124›Full record

ArticleDrug and alcohol review2025

Excess mortality in people hospitalised for alcohol use disorders before and during the pandemic - A registry-based retrospective cohort study.

Ladislav Kážmér, Ondřej Šíba, Barbora Orlíková

Abstract read
In one paragraph

Article in Drug and alcohol review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ladislav KážmérNational Institute of Mental Health, Klecany, Czech Republic.ORCID 0000-0001-9369-7721
Ondřej ŠíbaNational Institute of Mental Health, Klecany, Czech Republic.ORCID 0009-0009-4989-4504
Barbora OrlíkováNational Institute of Mental Health, Klecany, Czech Republic.ORCID 0000-0003-4488-4787

Funding

Agentura pro zdravotnický výzkum České Republiky NU22-D-146Ministry of Education, Youth and Sports of the Czech Republic, the Operational Programme Johannes Amos Comenius (OP JAC) CZ.02.01.01/00/22_008/0004583
6 · The paper itself

Abstract

introductionThe aim was to analyse mortality and estimate the life expectancy among people hospitalised for alcohol use disorders (AUD) compared with the general Czech population aged ≥20 years. A temporal perspective on excess mortality was used, covering three recent calendar periods before and during the pandemic.

methodsThree retrospective cohorts of the target population were constructed using registry-based data. The target population was defined as all adult patients (aged ≥20 years) admitted to the hospital for AUD (ICD-10 dg. of F10.x) between 2010 and 2021. Age-adjusted mortality rates and life expectancies were calculated for the comparative analysis. Official Czech mortality and vital statistics were used for the comparison. A Poisson log-linear regression model was used to test the effect of the pandemic period (2020-2021) on mortality in the AUD target population.

resultsAt age 20, the estimated life expectancy of the AUD target was 21-27 years less than that of the Czech general population. Excess mortality was relatively highest in young people aged 20-34 years and in adults aged 35-49 years. During the pandemic period 2020-2021, mortality rates in the target AUD increased significantly. However, relative inequalities with the general Czech population did not change significantly. DISCUSSION AND

conclusionsPeople hospitalised for AUD have much higher mortality rates, resulting in markedly reduced life expectancy. During the pandemic, their mortality rates increased even more. However, the increase was no greater than in the general Czech population.

Indexed as

AlcoholismAlcohol-Related DisordersCOVID-19HospitalizationLife ExpectancyPandemicsAdultAgedCohort StudiesCzech RepublicFemaleHumansMaleMiddle AgedRegistriesRetrospective Studiesalcohol use disordersCOVID pandemiclife expectancymortality

Identifiers

PMID40134124
PMCPMC12117291

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.