Evidence map›Paper›PMID 40134020›Full record

ReviewCancer cell international2025

Migrasomes, critical players in intercellular communication.

Zhiyong Tan, Chadanfeng Yang, Shi Fu, Junchao Wu, Yinglong Huang, Haihao Li, Chen Gong, Dihao Lv, Jiansong Wang, Mingxia Ding and 1 more

Abstract readReview
In one paragraph

Review in Cancer cell international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhiyong Tan *Department of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.ORCID http://orcid.org/0000-0002-7771-0962
Chadanfeng Yang *Department of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Shi Fu *Department of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Junchao Wu *Department of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Yinglong Huang *Department of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Haihao Li *Department of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Chen GongDepartment of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Dihao LvDepartment of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Jiansong WangDepartment of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China.
Mingxia DingDepartment of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China. dingmingxia@kmmu.edu.cn.
Haifeng WangDepartment of Urology, Yunnan Institute of Urology, The Second Affiliated Hospital of Kunming Medical University, No. 347, Dianmian Street, Wuhua District, Kunming, Yunnan, 650101, People's Republic of China. t13085348360@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migrasomes are a newly discovered type of extracellular vesicle (EV) formed during cell migration, playing a pivotal role in intercellular communication. These vesicles are generated by retracting fibers of migrating cells and encapsulate various molecules, such as proteins, lipids, and RNA, allowing the transfer of biochemical signals to neighboring cells. Current evidence suggests that migrasomes are involved in a wide range of physiological processes such as embryogenesis, angiogenesis, immune modulation, and mitochondrial quality control. Moreover, migrasomes are implicated in pathological conditions, including cancer metastasis, cardiovascular diseases, and viral infections. To fully understand their significance, it is critical to first explore the molecular mechanisms underlying their formation and function. Recent studies have shed light on the biogenesis, release, and biological properties of migrasomes, all of which are key to understanding their role in cell-to-cell communication. In this review, we provide an up-to-date summary of migrasome biogenesis, release, characterization, and their biological activities in intercellular communication, while also proposing potential new functions for these vesicles.

Indexed as

Cell–cell communicationExtracellular vesiclesMigrasomePhysiological and pathological processes

Identifiers

PMID40134020
PMCPMC11934494

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.