Evidence map›Paper›PMID 40133929›Full record

ArticleBMC veterinary research2025

Prevalence and genetic characterization of feline leukemia virus in portuguese stray cats.

Pedro Morais de Almeida, Adriana Belas, Mauro Bragança, Joana de Oliveira, Carlos Viegas

Abstract read
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Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pedro Morais de AlmeidaFaculty of Veterinary Medicine, Lusófona University- Lisbon University Centre, Lisbon, Portugal. p3350@ulusofona.pt.
Adriana BelasFaculty of Veterinary Medicine, Lusófona University- Lisbon University Centre, Lisbon, Portugal.
Mauro BragançaEgas Moniz School of Health and Science, Almada, Portugal.
Joana de OliveiraFaculty of Veterinary Medicine, Lusófona University- Lisbon University Centre, Lisbon, Portugal.
Carlos ViegasAnimal and Veterinary Research Center (CECAV), University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal.

Funding

CECAV UIDP/00772/2020Universidade Lusófona de Humanidades e Tecnologias FMV-ULusófona - SUBgrFeLV (2022-2023)
6 · The paper itself

Abstract

backgroundWith its large stray population, Portugal had the highest prevalence of the Feline Leukemia Virus (FeLV) infection in Europe. Progressive infection is still high, especially in southern Europe. In addition to the viral load, the subgroup is a determining factor in the development of the various syndromes associated with this disease, which can be fatal, justifying the morbidity and mortality of this retrovirus. The aim of the study was to determine the prevalence of FeLV, the viral load and to identify the subgroup of circulating virus in stray cats in the Lisbon metropolitan area. This prospective study was conducted at the Veterinary Teaching Hospital of the FMV-ULusófona, from November 2022 to January 2023. Blood samples from 129 stray cats from the Lisbon metropolitan area were included. All samples were tested for p27 antigen detection and proviral DNA by qPCR. For the detection of FeLV subgroups (A, B and C) nested PCR was performed.

resultsThe results showed that at the time of enrollment, 8.5% (n = 11/129) of the cats tested positive for FeLV using p27 antigen and qPCR for proviral DNA. Considering the proviral DNA load, 90.9% (n = 10/11) of the FeLV infections were classified as "likely progressive infection" (> 4.0 × 10

conclusionsTo the best of our knowledge, this is the first study to research FeLV subgroups in Portugal. The prevalence of FeLV in this group was consistent with our expectations. However, the molecular characterization differed significantly from that observed in other countries. These results suggest that stray cats may not be the main epidemiological concern.

Indexed as

Cat DiseasesLeukemia, FelineLeukemia Virus, FelineRetroviridae InfectionsTumor Virus InfectionsAnimalsCatsDNA, ViralFemaleMalePortugalPrevalenceProspective StudiesProvirusesViral LoadDNA, ViralFeLVPhylogenetic diversitySouthern EuropeStray catsSubgroup classificationViral loadsVirus reservoir

Identifiers

PMID40133929
PMCPMC11938750

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.