Evidence map›Paper›PMID 40133812›Full record

ArticleBMC infectious diseases2025

A nationwide joint spatial modelling of simultaneous epidemics of dengue, chikungunya, and Zika in Colombia.

Laís Picinini Freitas, Mabel Carabali, Alexandra M Schmidt, Jorge Emilio Salazar Flórez, Brayan Ávila Monsalve, César García-Balaguera, Berta N Restrepo, Gloria I Jaramillo-Ramirez, Kate Zinszer

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laís Picinini FreitasÉcole de Santé Publique, Université de Montréal, Montréal, Canada. lais.picinini.freitas@umontreal.ca.
Mabel CarabaliDepartment of Epidemiology, Biostatistics and Occupational Health, Mcgill University, Montréal, Canada.
Alexandra M SchmidtDepartment of Epidemiology, Biostatistics and Occupational Health, Mcgill University, Montréal, Canada.
Jorge Emilio Salazar FlórezInfectious and Chronic Diseases Study Group (GEINCRO), San Martín University Foundation, Medellín, Colombia.
Brayan Ávila MonsalveFaculty of Medicine, Universidad Cooperativa de Colombia, Villavicencio, Colombia.
César García-BalagueraFaculty of Medicine, Universidad Cooperativa de Colombia, Villavicencio, Colombia.
Berta N RestrepoUniversidad CES, Instituto Colombiano de Medicina Tropical, Medellín, Colombia.
Gloria I Jaramillo-RamirezFaculty of Medicine, Universidad Cooperativa de Colombia, Villavicencio, Colombia.
Kate ZinszerÉcole de Santé Publique, Université de Montréal, Montréal, Canada.

Funding

CIHR 428107Fonds de Recherche du Québec - Santé 329874Natural Sciences and Engineering Research Council of Canada RGPIN-2024-04312Universidad Cooperativa de ​Colo​mb​ia INV3065Wellcome Trust 310728
6 · The paper itself

Abstract

backgroundChikungunya, and Zika emerged in the 2010s in the Americas, causing simultaneous epidemics with dengue. However, little is known of these Aedes-borne diseases (ABDs) joint patterns and contributors at the population-level.

methodsWe applied a novel Poisson-multinomial spatial model to the registered cases of dengue (n = 291,820), chikungunya (n = 75,913), and Zika (n = 72,031) by municipality in Colombia, 2014-2016. This model estimates the relative risk of total ABDs cases and associated factors, and, simultaneously, the odds of presence and contributors of each disease using dengue as a baseline category. This approach allows us to identify combined characteristics of ABDs, since they are transmitted by the same mosquitoes, while also identifying differences between them.

resultsWe found an increased ABDs risk in valleys and south of the Andes, the Caribbean coast, and borders, with temperature as the main contributor (Relative Risk 2.32, 95% Credible Interval, CrI, 2.05-2.64). Generally, dengue presence was the most probable among the ABDs, although that of Zika was greater on Caribbean islands. Chikungunya and Zika were more likely present than dengue in municipalities with less vegetation (Odds Ratio, OR, 0.75, 95%CrI 0.65-0.86, and 0.85, 95%CrI 0.74-0.99, respectively). Chikungunya tended to be present in more socially vulnerable areas than dengue (OR 1.20, 95%CrI 0.99-1.44) and Zika (OR 1.19, 95%CrI 0.95-1.48).

conclusionsImportant differences between the ABDs were identified and can help guide local and context-specific interventions, such as those aimed at preventing cases importation in border and tourism locations and reducing chikungunya burden in socially vulnerable regions.

Indexed as

Chikungunya FeverDengueEpidemicsZika Virus InfectionAedesAnimalsChikungunya virusColombiaFemaleHumansMaleMosquito VectorsSpatial AnalysisZika Virus

Identifiers

PMID40133812
PMCPMC11934603

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.