Evidence map›Paper›PMID 40133802›Full record

ArticleBMC microbiology2025

The change of long tail fibers expanded the host range of a T5-like Salmonella phage and its application in milk.

Xiaofeng Zheng, Xin Wang, Pei Li, Yu Zhou, Xihui Zhu, Zimeng Hu, Hui Wang, Mianmian Chen, Xiang Huo, Yingyu Liu and 1 more

Abstract read
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Isolation and characterization of a novelFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaofeng ZhengCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Xin WangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Pei LiCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Yu ZhouCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Xihui ZhuCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Zimeng HuCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Hui WangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China.
Mianmian ChenCollege of Animal Science and Technology, College of Veterinary Medicine of Zhejiang A&F University, 666 Wusu Street, Lin'an District, Hangzhou, Zhejiang Province, 311300, China.
Xiang HuoJiangsu Provincial Center for Disease Control and Prevention, Nanjing, 210009, China.
Yingyu LiuCollege of Veterinary Medicine, Xinjiang Agricultural University, Urumqi, 830052, China. xjlyy1028@163.com.
Wei ZhangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, China. vszw@njau.edu.cn.

Funding

Guizhou Province Science and Technology Plan Project QKH [2023]008Hainan Province key research and development project assignment ZDYF2022XDNY236Sanya Yazhou Bay Science and Technology City SCKJ-JYRC-2022-80The Guidance Foundation, the Sanya Institute of Nanjing Agricultural University NAUSY-MS12
6 · The paper itself

Abstract

We engineered novel T5-like bacteriophage (phage) with extended host ranges by editing the long-tail fibers (PB3 and PB4) to combat Salmonella Enteritidis. By replacing the long-tail fibers PB3 and PB4 regions of phage PH204 with those from phage SP76, we created phages RPA

Indexed as

Host SpecificityMilkSalmonella enteritidisSalmonella PhagesViral Tail ProteinsAnimalsBacteriolysisFood MicrobiologyHydrogen-Ion ConcentrationTemperatureViral Tail ProteinsHomologous recombinationHost range expansionSalmonellaT5-like phages

Identifiers

PMID40133802
PMCPMC11938639

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.