Evidence map›Paper›PMID 40133760›Full record

ReviewMolecular and cellular biochemistry2025

Roles of microRNAs in cardiorenal syndrome.

Yilin Ren, Hui Lin, Junnan Guo, Xiaole Su, Lihua Wang, Xi Qiao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular and cellular biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yilin Ren *Department of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Hui Lin *Department of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Junnan GuoDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Xiaole SuDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Lihua WangDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China.
Xi QiaoDepartment of Nephrology, Second Hospital of Shanxi Medical University, Taiyuan, People's Republic of China. qiaoxi7347@vip.163.com.ORCID http://orcid.org/0000-0002-4421-011X

Funding

Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province Grant no. 2017-29Research Project Supported by Shanxi Scholarship Council of China 2020-186
6 · The paper itself

Abstract

Cardiac and kidney diseases are intimately linked through numerous pathophysiological pathways, frequently exerting reciprocal influences on one another. This interconnection often culminates in heightened morbidity and mortality rates within the clinical spectrum of cardiorenal syndrome (CRS). CRS is categorized into five types based on the primary organ involved and the chronicity of the condition. Each type of CRS encompasses a complex array of pathophysiological mechanisms. In recent years, the field of microRNAs (miRNAs) has risen to prominence, playing a crucial role in the pathogenesis of a multitude of diseases. By uncovering novel therapeutic targets through the study of miRNAs that influence the expression of the CRS genes, the prognostic outcomes for patients could be significantly improved. This article provides a comprehensive review, examining the pathophysiological underpinnings of CRS, miRNAs alterations and their associated mechanisms in various forms of CRS, as well as the potential of miRNAs in precision medicine and the use of miRNAs for the diagnosis of the disease.

Indexed as

Cardio-Renal SyndromeGene Expression RegulationMicroRNAsAnimalsHumansMicroRNAsCardiorenal syndromeEpigenetic modificationsMicroRNAsMiRNA therapeutics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.