ArticleCommunications biology2025
Characterization of Arabidopsis thaliana thylakoid lumen 7.6 protein functions in photosystem II assembly.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Advances and opportunities for computational interrogation of plant proteins.The Plant journal : for cell and molecular biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
Cyclophilin 38 (CYP38) plays a crucial role in the assembly and stability of photosystem II (PSII), but its molecular mechanism remains unclear. In this study, we identified thylakoid lumen protein 7.6 (TLP7.6) as an in vivo interactor of CYP38. Under normal growth conditions, the tlp7.6 single mutant exhibited no significant phenotypic differences compared to wild-type Col-0. However, the cyp38-2/tlp7.6-1 double mutant displayed severe developmental defects, including stunted growth, delayed flowering, yellowish leaf, short primary roots, abnormal chloroplast ultrastructure, and reduced biomass, which were more pronounced than those in either the tlp7.6 or cyp38-2 single mutant. Photosynthetic analysis revealed that PSII capacities in cyp38-2/tlp7.6-1 and cyp38-2 mutants were significantly reduced, consistent with their slow-growth phenotype. Blue native PAGE analysis demonstrated a substantial reduction in PSII supercomplexes and light-harvesting complex II (LHCII) in cyp38-2/tlp7.6-1, while PSII monomer (PSII-M) were significantly increased. Immunoblotting and two-dimensional gel electrophoresis further confirmed decreased levels of key components of PSII, PSI, and ATPase subunits in the double mutant. Altogether, these results highlight the role of TLP7.6 as an assistive factor in CYP38-mediated PSII assembly, and provide insights into thylakoid lumen protein function in photosynthesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.