Evidence map›Paper›PMID 40133585›Full record

ArticleScientific reports2025

Sagittal balance analysis and treatment rationale for young patients with symptomatic lumbosacral transitional vertebrae.

Andreas Tsoupras, Romain Dayer, Hugo Bothorel, Antonio Faundez

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. How changes in segmental lordosis impact L1-pelvic-angle after adult spinal deformity surgery: Which lumbar levels matter most?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andreas TsouprasPaediatric Orthopaedics Unit, University Hospitals of Geneva, Geneva, Switzerland. andreas.tsoupras@gmail.com.
Romain DayerPaediatric Orthopaedics Unit, University Hospitals of Geneva, Geneva, Switzerland.
Hugo BothorelOrthopedic Surgery Department, Hôpital de la Tour, Meyrin, Switzerland.
Antonio FaundezOrthopedic Surgery Department, Hôpital de la Tour, Meyrin, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumbosacral transitional vertebrae (LSTV) are a common anomaly in 7-36% of the population. LSTV can contribute to mechanical low back pain and increase the risk of early degeneration in cranial segments due to hypermobility and stress. This study analyzed sagittal balance in young symptomatic LSTV patients and tried to identify compensatory mechanisms that may explain early degeneration. Nineteen symptomatic and skeletally mature subjects with LSTV were retrospectively identified. Imaging included standing biplanar spine radiographs and supine lumbar MRI. Sagittal balance parameters were measured, and LSTV were classified using the Castellvi classification. Vertical mid-vertebral angle differences were calculated using MRI and lateral radiographs. The cohort included 17 females and 2 males (mean age 16 ± 3 years). Mean pelvic incidence was 67°±8°. L1-S1 lordosis averaged 61°±10°, L4-S1 lordosis was 10° lower than expected, and L4-L5 lordosis was higher than literature values. Thirteen patients had L4-L5 discopathy, with nine showing additional abnormalities such as interspinous ligament edema or posterior facet hypertrophy. In our study, LSTV was associated with L5-S1 disc hypoplasia and altered lumbar lordosis, leading to compensatory L4-L5 hyperextension. These findings suggest early degeneration may result from abnormal lordosis distribution. Treatment should aim to optimize lordosis distribution to reduce stress on adjacent segments.

Indexed as

Lumbar VertebraeLumbosacral RegionPostural BalanceSacrumAdolescentAdultFemaleHumansLordosisLow Back PainMagnetic Resonance ImagingMaleRetrospective StudiesYoung AdultLordosis restorationLumbosacral transitional vertebraeSagittal balanceSurgical planning

Identifiers

PMID40133585
PMCPMC11937229

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.