ArticleScientific reports2025
Integration of the fluorescence based portable device with the AI tools for the real-time monitoring of oral mucosal lesions.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Study of the Spectral-Luminescent Properties of Saliva in Patients With Lung Cancer.Journal of biophotonics · 2026Article
- Clinical Applications and Diagnostic Performance of Adjunctive Light-Based Optical Technologies in Oral Potentially Malignant Disorders and Squamous Cell Carcinoma: A Systematic Review.Journal of clinical medicine · 2026Review
- Effectiveness of a Community-Based Oral Cancer Screening Program Using Portable Fluorescence Spectroscopy in Rural Madhya Pradesh, India.Journal of pharmacy & bioallied sciences · 2025Article
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Authors and funding
2 authors.
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Abstract
There is a need for non-invasive, sensitive, real-time, and user-friendly optical devices integrated with artificial intelligence (AI) based tools for the detection of oral mucosal lesions at early stage. Research on the development of optical devices has been executed by several research groups for the cancer detection and it is still being continued. We have also contributed towards it by developing a steady- state fluorescence-based portable device. The in-house developed device is equipped with 405 nm laser diode, UV visible spectrometer, optical components, and other accessories. Laser light irradiated on the oral cavity of diseased (cancerous) and non-diseased (normal) groups, excites the two endogenous fluorophores namely FAD and porphyrin. We observed an enhancement in the porphyrin fluorescence of cancerous patients (OSCC and Dysplasia) than the normal group. Data analysis carried out by AI tools i.e., Naïve Bayes, LDA, and QDA showed slightly higher accuracy for QDA. QDA was able to discriminate among Normal to OSCC, Normal to Dysplasia, and Dysplasia to OSCC with accuracies of 95.34%, 100%, and 97.43% respectively.
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