ArticleScientific reports2025
Effects of monoglyceride blend on performance and intestinal health status of piglets fed diets without growth promoters.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The study aimed to evaluate the effects of supplementing monoglyceride blend in diets without growth promoters on performance, diarrhea occurrence, blood profile, intestinal morphology and pH, mRNA expression of nutrient transporters, inflammatory markers, antioxidant enzymes, and junction proteins in weaned piglets. Forty piglets were randomly allocated to five groups fed the following diets: control (C), or supplemented with 0.75 g/kg of a blend of fatty acids in powder form (PA), or with 3.00 g/kg of a blend of fatty acids in powder form (HPA), or with 0.50 g/kg of a blend of fatty acids in liquid form (LA), or with 2.00 g/kg of a blend of fatty acids in liquid form (HLA). The LA and PA diets reduced (P < 0.05) the occurrence of diarrhea. The pH of intestinal contents was reduced (P < 0.05) in piglets fed monoglycerides blend. Fecal E. coli count tended (0.05 ≤ P < 0.1) to be reduced in piglets receiving all supplemented diets. LA diet increased (P < 0.05) villus height in the duodenum, while others tended to increase it (0.05 ≤ P < 0.1). In the jejunum, all supplemented diets increased (P < 0.05) the goblet cell proportion. In the ileum, PA diet reduced (P < 0.05) crypt depth and increased (P < 0.05) villus: crypt ratio, and PA, HPA, and HLA diets increased (P < 0.05) goblet cell proportion. In the ileum, HPA and LA diets tended to reduce (0.05 ≤ P < 0.1) crypt depth and Peyer's patch. In the jejunum, LA and HLA diets increased (P < 0.05) the expression of Occludin and HPA increased the expression of Interleukin-10. In conclusion, the supplementation with a monoglyceride blend improves intestinal health and morphology, and local immune response in piglets fed diets without growth promoters.
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