ArticleScientific reports2025
MDCT evaluation of dynamic changes in aortic root parameters during the cardiac cycle in patients with aortic regurgitation.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the dynamic changes in multiple planes and parameters of the aortic root region at different phases of the cardiac cycle in patients with aortic regurgitation (AR) using multi-detector row computed tomography (MDCT). To provide more reference information and research foundation for preoperative MDCT evaluation of patients with aortic regurgitation undergoing Transcatheter Aortic Valve Replacement (TAVR).
methodsUsing MDCT, measurements were taken at the aortic annulus (AA), left ventricular outflow tract (LVOT), and sinotubular junction (STJ) during different phases of the cardiac cycle, including early systole, late systole, early diastole, and late diastole. The analyzed parameters included area, perimeter, diameter derived from area (DA), diameter derived from circumference (DC), long axis, short axis, and average diameter at each phase for each location. The dynamic changes in these parameters were then analyzed.
resultsAt the AA, the early systolic area, perimeter, DA, DC, and average diameter reached their maximum values, which were significantly greater than those in early diastole (P < 0.05). At the LVOT, the morphological parameters including area, perimeter, DC, DA, and long diameter reached their maximum values in late diastole, with no significant differences compared to early or late systole (P > 0.05). However, significant differences were observed between late diastole and early diastole (P < 0.05).At the STJ, the area, perimeter, DA, DC, long diameter, short diameter, and average diameter reached their maximum values in late systole, but there were no significant differences compared to early systole or early diastole (P > 0.05), while the difference from late diastole was significant (P < 0.05).
conclusionIn patients with AR, the measurement parameters of the AA、LVOT and the STJ are critical for the success of TAVR.Preoperative prosthesis selection for TAVR can still be based on MDCT measurements taken during early systole at the AA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.