Evidence map›Paper›PMID 40133259›Full record

ArticleNature communications2025

Eating disorder symptoms and emotional arousal modulate food biases during reward learning in females.

Nina Rouhani, Cooper D Grossman, Jamie Feusner, Anita Tusche

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nina RouhaniDepartment of Psychology, University of Southern California, Los Angeles, CA, 90089, USA. nrouhani@usc.edu.
Cooper D GrossmanDivision of the Humanities and Social Sciences, California Institute of Technology, Pasadena, CA, 91125, USA.
Jamie FeusnerDepartment of Psychiatry, University of Toronto, Toronto, ON, M5T 1R8, Canada.
Anita TuscheDepartment of Psychology, Queen's University, Kingston, ON, K7L 3N6, Canada.ORCID http://orcid.org/0000-0003-4180-8447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food seeking and avoidance engage primary reward systems to drive behavior. It is nevertheless unclear whether innate or learned food biases interact with general reward processing to interfere with goal-directed choice. To this end, we recruited a large non-clinical sample of females with high eating-disorder symptoms ('HED') and a matched sample of females with low eating-disorder symptoms ('LED') to complete a reward-learning task where the calorie content of food stimuli was incidental to the goal of maximizing monetary reward. We find and replicate a low-calorie food bias in HED and a high-calorie food bias in LED, reflecting the strength of pre-experimental food-reward associations. An emotional arousal manipulation shifts this group-dependent bias across individual differences, with interoceptive awareness predicting this change. Reinforcement-learning models further identify distinct cognitive components supporting these group-specific food biases. Our results highlight the influence of reinforcement-based mechanisms and emotional arousal in eliciting potentially maladaptive food-reward associations.

Indexed as

ArousalEmotionsFeeding and Eating DisordersLearningRewardAdolescentAdultFeeding BehaviorFemaleFoodHumansReinforcement, PsychologyYoung Adult

Identifiers

PMID40133259
PMCPMC11937311

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.