Evidence map›Paper›PMID 40133238›Full record

ReviewMicrobial biotechnology2025

Understanding Efflux-Mediated Multidrug Resistance in Botrytis cinerea for Improved Management of Fungicide Resistance.

Zhaochen Wu, Junting Zhang, Jianjun Hao, Pengfei Liu, Xili Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Microbial biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Functional and Genomic Characterization ofPlants (Basel, Switzerland) · 2026
    Article
  2. Secreted proteins fromFrontiers in plant science · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhaochen WuDepartment of Plant Pathology, China Agricultural University, Beijing, China.ORCID https://orcid.org/0009-0006-6869-6712
Junting ZhangDepartment of Plant Pathology, China Agricultural University, Beijing, China.
Jianjun HaoSchool of Food and Agriculture, University of Maine, Orono, Maine, USA.
Pengfei LiuDepartment of Plant Pathology, China Agricultural University, Beijing, China.
Xili LiuDepartment of Plant Pathology, China Agricultural University, Beijing, China.

Funding

National Key Research and Development Program of China 2022YFD1400900
6 · The paper itself

Abstract

Botrytis cinerea is a major fungal pathogen infecting over 1400 plant species. It poses a significant threat to agriculture due to multiple fungicide resistance and multidrug resistance, involves resistance to fungicides with different modes of action. Multiple fungicide resistance is mostly due to an accumulation of point mutations in target genes over time, and MDR is result from efflux (e-MDR) and metabolism (m-MDR). This review introduces the occurrence of e-MDR of B. cinerea, the key mechanisms, origins and management strategies of e-MDR in fields. New materials such as nanomaterials become a strategy to overcoming MDR via inhibition of ABC transporter. A deeper understanding of efflux-mediated MDR will provide a support for the MDR management of B. cinerea and the efficient utilization of fungicides.

Indexed as

BotrytisDrug Resistance, FungalDrug Resistance, Multiple, FungalFungicides, IndustrialPlant DiseasesFungicides, Industrial

Identifiers

PMID40133238
PMCPMC11936762

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.