Evidence map›Paper›PMID 40133135›Full record

Trial reportInternational psychogeriatrics2026

Psychological characteristics and functional abilities in older adults with subjective cognitive complaints: A potential new target for early intervention.

Jaclyn M Fox, Danielle J Harvey, Christine N Pons, Yichu Chen, Samina Rahman, Michael J Ryan, Jagnoor Randhawa, Alyssa M Weakley, Michelle L Chan, Maureen Schmitter-Edgecombe and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International psychogeriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jaclyn M FoxUniversity of California, Davis Department of Neurology, Sacramento, USA. Electronic address: jmfox@ucdavis.edu.
Danielle J HarveyUniversity of California, Davis Department of Public Health Sciences, Davis, USA.
Christine N PonsUniversity of California, Davis School of Medicine, Sacramento, USA.
Yichu ChenUniversity of California, Davis Department of Public Health Sciences, Davis, USA.
Samina RahmanWashington State University, Department of Psychology, Pullman, USA.
Michael J RyanUniversity of California, Davis Department of Neurology, Sacramento, USA.
Jagnoor RandhawaUniversity of California, Davis Department of Neurology, Sacramento, USA.
Alyssa M WeakleyUniversity of California, Davis Department of Neurology, Sacramento, USA.
Michelle L ChanUniversity of California, Davis Department of Neurology, Sacramento, USA.
Maureen Schmitter-EdgecombeWashington State University, Department of Psychology, Pullman, USA.
Sarah Tomaszewski FariasUniversity of California, Davis Department of Neurology, Sacramento, USA.

Funding

Brain pathologies, reserve and cognition in aging and dementiaR01AG031563 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Evan Fletcher, SARAH E TOMASZEWSKI-FARIAS · 2009 to 2026
$8.9M
Compensation Training and Lifestyle Modifications to promote healthy aging in persons at risk for Alzheimer's disease: a digital application supported interventionR01AG066748 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SCHMITTER-EDGECOMBE, MAUREEN, TOMASZEWSKI-FARIAS, SARAH E · 2021 to 2025
$4.2M
NIA NIH HHS R01 AG031563NIA NIH HHS R01 AG066748
6 · The paper itself

Abstract

objectivesPositive psychological characteristics may help to bolster daily functioning in older adults even in the presence of subjective or subtle objective cognitive weaknesses. The purpose of the present study was to examine which specific psychological characteristics may contribute to better functional abilities, independent of cognitive performance, among a sample of older adults with subjective cognitive decline (SCD). DESIGN, SETTING, AND

participantsParticipants included 277 older adults recruited from the community who were enrolled in a randomized controlled trial examining the impact of training in memory support strategies and healthy lifestyle behaviors. The current study was based on baseline data prior to intervention randomization. MEASUREMENTS: Linear regression was used to assess associations between positive psychological characteristics (positive affect, life satisfaction, purpose in life, resiliency, self-management of health, and perceived competence), one negative psychological characteristic (negative affect), and functional abilities controlling for demographic variables. A final model assessed for associations between functional abilities and any of the significant characteristics identified in the linear regressions while controlling for global cognition (measured with the Modified Neuropsychological Test Battery composite score), depression, and demographic variables.

resultsIn the individual regressions, most of the psychological characteristics were significantly associated with functional abilities. In the final model, positive and negative affect remained significantly associated with functional abilities.

conclusionsThis is one of the first studies to show that greater positive affect is associated with better functional abilities, even after controlling for objective cognitive performance. Positive affect in older adults may represent a modifiable target for intervention.

Indexed as

Activities of Daily LivingCognitive DysfunctionAgedAged, 80 and overCognitionDepressionFemaleHumansLinear ModelsMaleNeuropsychological TestsPersonal SatisfactionAgingFunctional abilitiesPositive and negative affectPositive psychological characteristicsSubjective cognitive decline

Identifiers

PMID40133135
PMCPMC12353411

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.