ArticleEmerging infectious diseases2025
Prevalence of Herpes B Virus in Wild Long-Tailed Macaques, Thailand, 2018-2024.
Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Comprehensive genomic characterization of herpes B virus isolated from a wild long-tailed macaque reveals conserved entry mechanisms and zoonotic potential.Emerging microbes & infections · 2026Article
- Non-Human Primates as Sentinels and Reservoirs of Emerging Zoonotic Diseases in Indonesia: A One Health Perspective on Pathogen Spillover, Surveillance Gaps, and Regulatory Frameworks.Journal of medical primatology · 2026Review
- Development and Proof-of-Concept Analytical Validation of a HotStart Loop-Mediated Isothermal Amplification (LAMP) Assay Targeting the UL1 Gene forVeterinary sciences · 2026Article
- Herpes B virus and the neglected risk of zoonotic spillover.One health (Amsterdam, Netherlands) · 2026Review
- Updated practice for detection of viral infections in breeding macaques.Zoological research · 2025Review
- A narrative review of monkey B virus (Clinical and experimental vaccine research · 2025Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herpes B virus (B virus) is an enigmatic zoonotic virus that has caused severe neurologic symptoms in humans exposed to captive macaques used for experimentation. We examined 864 wild long-tailed macaques from 22 locations across Thailand for B virus infection. All 22 macaque populations tested positive for B virus antibodies; seropositivity ranged from 25% to 100%. B virus shedding was detected in 9 (1.04%) oral swab samples by using quantitative PCR of the virus UL29 gene. We phylogenetically analyzed partial genome sequences of B virus (US5-US6 genes) from 6 of the PCR-positive samples. All 6 sequences were clustered in clade II, which includes B virus strains from rhesus, Japanese, and long-tailed macaques, suggesting co-evolution of B virus with macaques. Continued surveillance and sequencing of B virus in macaque populations will be needed to prevent B virus transmission to humans and to develop appropriate vaccines to prevent human B virus infections.
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