ArticleEmerging infectious diseases2025
Epidemiology of Tularemia among Humans and Animals, Baden-Wuerttemberg, Germany, 2012-2022.
Article in Emerging infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Tick-borne tularaemia as a differential diagnosis in ulcerative skin infection and regional lymphadenopathy in children: a case report.Journal of medical case reports · 2026Article
- Article
- Tularemia: Historical Perspectives and Current Challenges of a Re-Emerging Zoonosis.Biomedicines · 2026Review
- Retrospective multicenter analysis of causes of death in wild mammals in Southern Germany (2019-2023).Frontiers in veterinary science · 2026Article
- The European Union One Health 2024 Zoonoses Report.EFSA journal. European Food Safety Authority · 2025Article
- Country-wide assessment of tick-borne pathogens collected in ticks between 2021 and 2024 in Germany, with a focus onOne health (Amsterdam, Netherlands) · 2025Article
- Clinical Characteristics and Treatment Strategies in a Cohort of Patients with Tularemia: A Retrospective Multicenter Analysis of 65 Cases in Germany.Antibiotics (Basel, Switzerland) · 2025Article
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Authors and funding
8 authors.
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Abstract
Tularemia, a zoonosis caused by Francisella tularensis, is endemic in Baden-Wuerttemberg, Germany. To determine tularemia epidemiology in this region, we characterized the genetic diversity of F. tularensis in human and animal isolates during 2012-2022 by using whole-genome sequencing, combined with human and veterinary surveillance data analysis. Human case numbers varied; most cases occurred in 2021 (n = 34). Arthropod bites were reported most in cases with information on animal exposure (45%, n = 43). Poisson regression confirmed a significant increase in human cases during the study period (p<0.001). No seasonal pattern was identified, but case numbers were lowest in winter. Human surveillance data often lacked exposure details. Positivity rates in animals were 5%-34%, increasing since 2017. Human isolates often clustered with hare-derived strains, although transmission routes often remain unclear. These findings emphasize the importance of combining genome sequencing with detailed epidemiologic tracing to identify infection sources and improve surveillance data.
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