Evidence map›Paper›PMID 40132525›Full record

ArticleInternational journal of surgery case reports2025

Bone tumors in the maxilla and the tibia leading to the diagnosis of asymptomatic primary hyperparathyroidism in a 17-year-old male: A case report.

Saja Karaja, William Borghol, Ahed Assaf, Nabeha Haytham Alibrahim, Maram Alkirwan, Rana Shannat

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Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Saja KarajaFaculty of Medicine, Hama University, Hama, Syria.
William BorgholFaculty of Medicine, Hama University, Hama, Syria.
Ahed AssafFaculty of Medicine, Hama University, Hama, Syria. Electronic address: ahd.assaf.2019@gmail.com.
Nabeha Haytham AlibrahimDepartment of Dermatology, Hama National Hospital, Hama, Syria.
Maram AlkirwanDepartment of Endocrinology, Hama National Hospital, Hama, Syria.
Rana ShannatDepartment of Endocrinology, Faculty of Medicine, Hama University, Hama, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPrimary hyperparathyroidism is a common endocrine disorder, especially among postmenopausal women, characterized by elevated calcium levels and excessive secretion of parathyroid hormone due to hyperactive parathyroid glands. PRESENTATION OF CASE: A 17-year-old male presented with a painless mass in the maxilla, which developed six months after a cystic lesion was diagnosed in his right knee. Subsequent examinations identified a parathyroid tumor, leading to surgical excision of the right lower parathyroid gland, and the patient developed hypocalcemia postoperatively, indicative of Hungry Bone Syndrome. DISCUSSION: Primary hyperparathyroidism occurs mostly in females aged 50 to 60 and presents with many clinical symptoms and signs, but our patient was a 17-year-old male and had one of the complications of this disease, which is a brown tumor, without the appearance of the common typical symptoms of the disease, which led to excluding the diagnosis of a brown tumor and suspecting a giant cell tumor due to the histological similarity.

conclusionThis case report emphasizes the critical need to consider primary hyperparathyroidism in atypical demographics, such as young males. Notably, the formation of a brown tumor prior to overt hyperparathyroidism symptoms suggests potential early complications. This case reinforces the importance of surgical expertise in successful parathyroidectomy in countries without advanced imaging.

Indexed as

Brown tumorCase reportEndocrine disordersGiant cell tumorHyperparathyroidismParathyroid hormone (PTH)

Identifiers

PMID40132525
PMCPMC12138517

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