ArticlePloS one2025
Impact of double-bolus tracking to individualize scan timing of the portal venous phase in preoperative computed tomography colonography angiography for right-sided colon cancer.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Optimization of contrast medium dosing using a body surface area-based protocol for preoperative CT colonography-angiography.Abdominal radiology (New York) · 2026Article
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17 authors.
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Abstract
aimIn computed tomography colonography angiography (CTC-A), used for preoperative screening of right-sided colon cancer, the timing of venous phase imaging is conventionally determined by a fixed-delay time; however, the contrast effect may be insufficient because of individual differences in blood flow status. Therefore, we developed the double-bolus tracking (DBT) method to solve this issue.
methodWe compared the contrast effect and image quality of the portal venous systems between two methods of the conventional fixed-delay and DBT which utilizes low-dose monitoring to individualize venous scan timings. Data from 30 consecutive patients who underwent CTC-A for right-sided colon cancer using the DBT method were prospectively collected and compared with that from 30 consecutive patients who underwent the conventional fixed-delay method between August 2018 and July 2022. CT values of the portal vein, gastrocolic trunk, and middle colic veins were measured. Additionally, two gastrointestinal surgeons performed a five-point visual evaluation of the three-dimensional volume rendering image of the gastrocolic trunk.
resultsCT values in the DBT group were significantly higher than those in the fixed-delay group. (portal vein: 266.7 HU vs. 210.0 HU; p < 0.001, gastrocolic trunk: 251.6 HU vs. 191.0 HU; p < 0.001, middle colic vein: 257.2 HU vs. 190.1 HU; p < 0.001). Visual assessment of the gastrocolic trunk was significantly higher in the DBT group than that in the fixed-delay group (DBT, 3.6, 3.4; fixed-delay, 2.6, 2.8; p = 0.003, p = 0.044).
conclusionThe DBT method can enhance the contrast effect of the portal venous systems and improve image quality.
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