Evidence map›Paper›PMID 40131667›Full record

ArticleMolecular imaging and biology2025

Ex-vivo Imaging of Glial Energy Metabolism in the Neonatal Mouse Brain during Convulsive Seizures with Intranasal Radiotracer Administration.

Rie Hosoi, Kenya Tada, Takahiro Hayakawa, Yuka Haga

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular imaging and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rie HosoiDivision of Health Sciences, Graduate School of Medicine, University of Osaka, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan. hosoi@sahs.med.osaka-u.ac.jp.ORCID http://orcid.org/0000-0002-4646-9272
Kenya TadaDivision of Health Sciences, Graduate School of Medicine, University of Osaka, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Takahiro HayakawaDivision of Health Sciences, Graduate School of Medicine, University of Osaka, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yuka HagaDivision of Health Sciences, Graduate School of Medicine, University of Osaka, 1-7 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, we examined changes in glial energy metabolism in neonatal mouse brain images obtained under pathological conditions following intranasal administration of the radiotracer [2- PROCEDURES: [2-

resultsIntranasally administered [2-

conclusionsQuantitative images of biological functions in the neonatal mouse brain can be obtained by intranasal administration. This technique allowed the observation of a decrease in acetate uptake associated with convulsive seizures. The results of this study could be applied to the imaging of biological brain functions and research on neurological disorders using labeled probes in neonatal mice.

Indexed as

BrainEnergy MetabolismNeurogliaSeizuresAcetatesAdministration, IntranasalAnimalsAnimals, NewbornAutoradiographyMiceMice, Inbred C57BLRadioactive TracersAcetatesRadioactive TracersGliaIntranasal administrationNeonatal mouse brainPentylenetetrazoleSeizure

Identifiers

PMID40131667
PMCPMC12162742

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.