Evidence map›Paper›PMID 40131610›Full record

ArticleChinese journal of integrative medicine2025

Effect of Bushen Huoxue Granule on Clearance of Pathological α-Synuclein in MPP

Zhen-Xian Luan, Xiang-Lin Tang, Fei-Ran Hao, Min Li, Shao-Dan Li, Ming-Hui Yang

Abstract read
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In one paragraph

Article in Chinese journal of integrative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhen-Xian LuanMedical Department of Traditional Chinese Medicine, the Sixth Medical Center of the PLA General Hospital, Beijing, 100048, China.
Xiang-Lin TangMedical Department of Traditional Chinese Medicine, the Sixth Medical Center of the PLA General Hospital, Beijing, 100048, China.
Fei-Ran HaoMedical Department of Traditional Chinese Medicine, the Sixth Medical Center of the PLA General Hospital, Beijing, 100048, China.
Min LiMedical Department of Traditional Chinese Medicine, the Sixth Medical Center of the PLA General Hospital, Beijing, 100048, China.
Shao-Dan LiMedical Department of Traditional Chinese Medicine, the Sixth Medical Center of the PLA General Hospital, Beijing, 100048, China.
Ming-Hui YangMedical Department of Traditional Chinese Medicine, the Sixth Medical Center of the PLA General Hospital, Beijing, 100048, China. Ymh9651@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of Bushen Huoxue Granule on the ubiquitin-proteasome system (UPS) in an in vitro model of Parkinson's disease.

methodsAfter treated with 1-methyl-4-phenylpyridinium (MPP

resultsBCS (volume fraction ⩽20%) intervention could alleviate the MMP

conclusionBCS intervention protected UPS function, increased 20S proteasome activity, promoted pathological α-syn clearance, restored cell viability, and reversed the damage caused by MPP

Indexed as

1-Methyl-4-phenylpyridiniumalpha-SynucleinDrugs, Chinese HerbalAnimalsCell SurvivalPC12 CellsPhosphorylationProteasome Endopeptidase ComplexRatsTyrosine 3-MonooxygenaseUbiquitin1-Methyl-4-phenylpyridiniumalpha-SynucleinDrugs, Chinese HerbalProteasome Endopeptidase ComplexTyrosine 3-MonooxygenaseUbiquitin1-methyl-4-phenylpyridiniumBushen Huoxue GranuleChinese medicineParkinson’s diseaseubiquitin-proteasome systemα-synuclein

Identifiers

PMID40131610

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.