Evidence map›Paper›PMID 40131562›Full record

ArticleClinical oral investigations2025

Varying responses to periodontal treatment in different extent of plaque-induced gingivitis: a prospective cohort study.

Xuan Ying, Yue Dai, Guannan Bai, Zijian Cheng, Xia Cai

Abstract read
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In one paragraph

Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuan YingDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, Zhejiang, China.
Yue DaiDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, Zhejiang, China.
Guannan BaiDepartment of Child Health Care, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, 310052, Zhejiang, China.
Zijian ChengDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, Zhejiang, China. zj_cheng@zju.edu.cn.
Xia CaiDepartment of Periodontology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Hangzhou, 310000, Zhejiang, China. cxshidou@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare the clinical response to periodontal treatment in localized and generalized gingivitis using periodontal variables and patient-reported outcomes (PROs). MATERIALS AND

methodsSixty participants (30 with localized gingivitis, 30 with generalized gingivitis) underwent scaling, polishing, and oral hygiene instruction at baseline and monthly follow-ups until periodontal health was restored. Periodontal variables (bleeding on probing [BOP], gingival index [GI], and plaque index [PLI]) along with PROs on oral hygiene practices and the Self-Efficacy Scale for Self-Care (SESS) were assessed.

resultsAt 1-month follow-up, generalized gingivitis showed significantly greater improvements in BOP (p < 0.001) and GI (p < 0.001) versus localized gingivitis, with no intergroup difference in PLI reduction (p = 0.747). Periodontal health was achieved in 80% of localized cases versus 30% of generalized cases after single-session therapy (p < 0.001), with 70% of generalized cases requiring multiple re-treatments. Unresolved generalized cases had higher baseline BOP (p = 0.014) but similar baseline PLI (p = 0.322) and no significant differences in treatment-induced BOP (p = 0.137) or PLI changes (p = 0.563). SESS scores improved significantly in both groups, with greater SE-D score improvement in localized cases. Localized gingivitis had higher baseline prolonged brushing rates (> 2 min: 66.7% vs. 33.3%), but post-intervention oral hygiene did not differ between groups.

conclusionsLocalized gingivitis responded well to single-session therapy, whereas generalized gingivitis required multiple treatments due to higher baseline inflammation, emphasizing the need for distinct clinical strategies. CLINICAL RELEVANCE: This study supports subtype-specific management in gingivitis, advocating single-session therapy for localized cases and staged interventions for generalized cases to optimize outcomes and reduce overtreatment.

Indexed as

Dental PlaqueGingivitisAdultDental Plaque IndexDental ScalingFemaleHumansMaleMiddle AgedOral HygienePatient Reported Outcome MeasuresPeriodontal IndexProspective StudiesTreatment OutcomeGingivitisOral hygiene instructionsPatient-reported outcomesPeriodontal healthProfessional mechanical plaque removal (PMPR)

Identifiers

PMID40131562

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.