Evidence map›Paper›PMID 40131517›Full record

ArticleInternational ophthalmology2025

Effect of long-term silicone oil tamponade on the density of blood vessels in the macular and peripapillary region in patients with rhegmatogenous retinal detachment.

Zhiru Zhang, Xueqin Zhang, Tianyu Yao, Jie Chen, Li Huang, Chen Qiu, Guihong Wu, Wei Yang, Yue He

Abstract read
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In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiru ZhangDepartment of Ophthalmology, People's Hospital of Deyang City, Deyang, 618000, Sichuan, People's Republic of China.
Xueqin ZhangDepartment of Ophthalmology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China.
Tianyu YaoDepartment of Ophthalmology, The Second People'S Hospital of Yibin, Yibin, 644000, Sichuan, People's Republic of China.
Jie ChenDepartment of Rheumatology and Immunology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China.
Li HuangSichuan Vocational College of Health and Rehabilitation, Zigong, 643000, Sichuan, People's Republic of China.
Chen QiuDepartment of Ophthalmology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China.
Guihong WuDepartment of Ophthalmology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China.
Wei YangDepartment of Ophthalmology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China.
Yue HeDepartment of Ophthalmology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan, People's Republic of China. hylyfy@163.com.

Funding

Scientific Research Topics of Sichuan Health and Family Planning Commission 16PJ560
6 · The paper itself

Abstract

objective purposeTo use optical coherence tomography angiography (OCTA) to evaluate changes in microvascular parameters in the macular and peripapillary areas of patients with rhegmatogenous retinal detachment (RRD) who received silicone oil (SO) tamponade for 6 months after vitrectomy.

methodsTwenty-one eyes (21 patients) with macular-off RRD treated with pars plana vitrectomy (PPV) and SO tamponade were reviewed. All patients underwent OCTA to measure the vascular density (VD) and perfusion density (PD) in the superficial capillary plexus (SCP), and optical coherence tomography to measure the central macular thickness (CMT) and retinal nerve fiber layer (RNFL) thickness throughout the 6-month postoperative period. Healthy fellow eyes were used as the control.

resultsThe vessel density and perfusion density of the whole area in the macular and peripapillary between the operated and control eye at 1, 3, and 6 months postoperatively were significantly different (all p < 0.05). Compared to the contralateral eyes, the CMT (all p < 0.001) and RNFL (all p < 0.05) of the RRD eyes were significantly thinner. During the follow-up period, both the SCP VD and SCP PD in the macular area of the RRD eyes decreased with time (all p < 0.05).

conclusionIn patients with RRD who underwent PPV and intraocular SO tamponade, the retinal SCP VDs and PDs gradually decreased over time. CMT and RNFL were decreased compared with contralateral eye.

Indexed as

EndotamponadeMacula LuteaOptic DiskRetinal DetachmentRetinal VesselsSilicone OilsVitrectomyAdultAgedFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleMiddle AgedSilicone OilsOptical coherence tomography angiographyRetinal perfusionRhegmatogenous retinal detachmentSilicone oil tamponade

Identifiers

PMID40131517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.