ReviewNaunyn-Schmiedeberg's archives of pharmacology2025
Bibliometric and visual analysis of drug-specific immunotherapy from 1990 to 2024.
Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Emerging trends and hotspots in Oseltamivir resistance: insights from a bibliometric investigation.Naunyn-Schmiedeberg's archives of pharmacology · 2026Pooled it
- The evolution and frontiers of global pediatric glucocorticoids research: an in-depth analysis based on 28 years of bibliometrics.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Icariin Modulates the Reproductive-Immune Axis: Molecular Insights and Therapeutic Potential.Current issues in molecular biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Specific immunotherapy (SIT) is key in allergic diseases, tumor immunity, and autoimmune regulation. In recent years, the mechanism of action of drugs in SIT has attracted much attention, including the induction of hypersensitivity responses and modulation of immune tolerance. However, scientific challenges remain regarding their mechanism of action and optimization strategies. Studies on pharmacological SIT have been accumulated in the past, and there is an urgent need for bibliometric analyses to review and prospect these results for future academic development. Strict search criteria were developed to screen and download literature information from the Web of Science Core Collection. Six elements of the included literature were analyzed and visualized using Citespace, VOSviewer software, and the Bibliometrix package. A total of 682 publications related to the drug SIT were included in this study. The growth trend in the number of publications is evident and entering a new phase with great potential for the future, with the highest total number of citations in 1998. The countries and institutions with the most publications were the USA and the University of Genoa. The author who contributed the most to the field was Incorvaia, Cristoforo. Moreover, Bousquet J was the most influential author. Allergy was considered the leading core source journal, and the Journal of Allergy and Clinical Immunology is the most influential. The reference with the highest outbreak intensity is Roberts G, 2018, Allergy, V73, P765, https://doi.org/10.1111/all.13317 . The analysis of the keywords by the various metrics shows that the research hotspot is the tumor-associated SIT, the cutting-edge topic is the mechanism of action of the drug AIT, and the respiratory SIT application is the cutting-edge hot issue. Drug SIT has made good progress with the joint participation of global research institutions, scientists, and various journals. However, cooperation and communication are weak, and it is necessary to build a new cooperation mode to promote the globalization of research results. We have found the research hotspots and cutting-edge issues in this field, which will guide us to make breakthroughs in a more precise direction and play the important role of drug safety in safeguarding human life and health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.