Evidence map›Paper›PMID 40131334›Full record

Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2025

Digital Skin Cancer Risk Reduction Interventions for Young Adults: Findings from a Hybrid Type-II Effectiveness-Implementation Trial.

Carolyn J Heckman, Elizabeth A Handorf, Anna Mitarotondo, Olga Khavjou, Sharon L Manne, Amy L Yaroch, Karen Glanz

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carolyn J HeckmanCancer Prevention and Control Program, Rutgers Cancer Institute, New Brunswick, New Jersey.ORCID 0000-0003-1016-3965
Elizabeth A HandorfDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health, Piscataway, New Jersey.ORCID 0000-0003-0445-8978
Anna MitarotondoCancer Prevention and Control Program, Rutgers Cancer Institute, New Brunswick, New Jersey.ORCID 0000-0002-4080-0307
Olga KhavjouHealth Economics Program, RTI International, Durham, North Carolina.ORCID 0000-0003-0805-0769
Sharon L ManneCancer Prevention and Control Program, Rutgers Cancer Institute, New Brunswick, New Jersey.ORCID 0000-0002-9304-7822
Amy L YarochCenter for Nutrition and Health Impact, Omaha, Nebraska.ORCID 0000-0001-9390-2449
Karen GlanzDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-0970-4931

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Eric Andrew Ross · 1985 to 2026
$138.8M
TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Modifying Young Adult Skin Cancer Risk and Protective Behaviors (UV4.me2):A Hybrid Type 2 Dissemination/Effectiveness TrialR01CA204271 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI HECKMAN, CAROLYN · 2017 to 2021
$2.9M
National Cancer Institute (NCI) P30CA006927National Cancer Institute (NCI) P30CA072720National Cancer Institute (NCI) R01CA204271NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA204271
6 · The paper itself

Abstract

backgroundEngagement in sun protection behaviors is low among young adults (ages 18-25 years). Efficacious sun safety interventions for this at-risk population and information on intervention engagement and costs are needed. The purpose was to conduct secondary analyses examining intervention implementation strategies and outcomes (e.g., engagement), intervention moderators, and costs of three digital interventions to increase sun protection behaviors previously evaluated for effectiveness in a randomized controlled trial.

methodsThe randomized controlled trial compared three conditions: a basic efficacious intervention, an enhanced version of the intervention, and an educational e-pamphlet. Sun protection measures, intervention engagement and implementation, putative moderators, and intervention costs were assessed through 1 year.

resultsEngagement (4.6 of 12 modules completed) was similar for basic and enhanced interventions. Engagement was significantly associated with sun protection. Men and individuals with lower tanning ability completed more modules than women and those with higher tanning ability. Enhanced was more effective than basic for men (but not women) through 1 year. After initial development, both active interventions were similar in cost per person at larger sample sizes.

conclusionsDespite attempts at enhancement, engagement in basic and enhanced was similar. Although all interventions were costly to create, they were less costly to maintain and could be scaled up for dissemination. Based on both engagement and effects on sun protection, the enhanced intervention would be recommended for men, women, or both. IMPACT: This digital intervention offers the potential to reduce skin cancer risk in a large population of US young adults.

Indexed as

Risk Reduction BehaviorSkin NeoplasmsAdolescentAdultFemaleHumansMaleSunscreening AgentsYoung AdultSunscreening Agents

Identifiers

PMID40131334
PMCPMC12133408

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.