Evidence map›Paper›PMID 40131228›Full record

ArticleACS biomaterials science & engineering2025

Establishing a Bioink Assessment Protocol: GelMA and Collagen in the Bioprinting of a Potential

Mariangela Rea, Luana Di Lisa, Giorgia Pagnotta, Nunzia Gallo, Luca Salvatore, Federica D'Amico, Noelia Campilio, José Manuel Baena, Juan Antonio Marchal, Arrigo F G Cicero and 2 more

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Three-dimensional-printed shape-memory composite scaffold for meniscus repair.The Journal of international medical research · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mariangela ReaDepartment of Chemistry 'Giacomo Ciamician' and INSTM UdR of Bologna, University of Bologna, 40129 Bologna, Italy.
Luana Di LisaDepartment of Chemistry 'Giacomo Ciamician' and INSTM UdR of Bologna, University of Bologna, 40129 Bologna, Italy.
Giorgia PagnottaDepartment of Chemistry 'Giacomo Ciamician' and INSTM UdR of Bologna, University of Bologna, 40129 Bologna, Italy.ORCID 0000-0002-8183-4992
Nunzia GalloDepartment of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.ORCID 0000-0003-1810-7917
Luca SalvatoreTypeone Biomaterials S.r.l., Via Europa 167, 73021 Calimera, Lecce, Italy.
Federica D'AmicoDepartment of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.
Noelia CampilioREGEMAT 3D S.L., 18016 Granada, Spain.
José Manuel BaenaREGEMAT 3D S.L., 18016 Granada, Spain.
Juan Antonio MarchalDepartment of Human Anatomy and Embryology, Faculty of Medicine, University of Granada, 18016 Granada, Spain.ORCID 0000-0002-4996-8261
Arrigo F G CiceroMedical and Surgery Sciences Department, University of Bologna, 40138 Bologna, Italy.
Claudio BorghiMedical and Surgery Sciences Department, University of Bologna, 40138 Bologna, Italy.
Maria Letizia FocareteDepartment of Chemistry 'Giacomo Ciamician' and INSTM UdR of Bologna, University of Bologna, 40129 Bologna, Italy.ORCID 0000-0002-0458-7836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen and gelatin methacryloyl (GelMA) are widely studied biomaterials for extrusion-based bioprinting (EBB) due to their excellent biological properties and ability to mimic the extracellular matrix of native tissues. This study aims to establish a preliminary workflow for approaching EBB by assessing collagen and GelMA printability and biological performance. GelMA was selected for its cost-effectiveness and ease of synthesis, while our collagen formulation was specifically optimized for printability, which is a challenging aspect of bioprinting. A parallel evaluation of their printability and biological performance is provided to develop a preliminary 3D intestinal model replicating the submucosa, lamina propria, and epithelial layer. Rheological analyses demonstrated that both materials exhibit a shear-thinning behavior. Collagen (u-CI) displayed a shear-thinning parameter

Indexed as

BioprintingCollagenGelatinIntestinesMethacrylatesBiocompatible MaterialsHumansHydrogelsInkPrinting, Three-DimensionalTissue EngineeringBiocompatible MaterialsCollagenGelatingelatin methacryloylHydrogelsMethacrylates3D bioprintingcollagenGelMAintestine bioprinted modelrheology

Identifiers

PMID40131228
PMCPMC12001187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.