Evidence map›Paper›PMID 40130256›Full record

ArticleFrontiers in medicine2025

Case report: Clinical management of freshwater stingray wounds using negative pressure therapy.

Janio J M Nattrodt, Victória A Bezerra-de-Freitas, Ana Paula S S Merval, Eloise T Filardi, Felipe A Cerni, Domingos S M Dantas, Alysson B M Lins, Luis E B Galan, Roberto C Carbonell, Manuela B Pucca

Abstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Janio J M NattrodtGeneral Hospital of Roraima, Boa Vista, Brazil.
Victória A Bezerra-de-FreitasMedical School, Federal University of Roraima (UFRR), Boa Vista, Brazil.
Ana Paula S S MervalGraduate Program in Health and Science (PROCISA), Federal University of Roraima (UFRR), Boa Vista, Brazil.
Eloise T FilardiGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.
Felipe A CerniMedical School, Federal University of Roraima (UFRR), Boa Vista, Brazil.
Domingos S M DantasPrograma Doutoral de Bioética da Faculdade de Medicina do Porto, Porto, Portugal.
Alysson B M LinsGeneral Hospital of Roraima, Boa Vista, Brazil.
Luis E B GalanGeneral Hospital of Roraima, Boa Vista, Brazil.
Roberto C CarbonellGeneral Hospital of Roraima, Boa Vista, Brazil.
Manuela B PuccaGraduate Program in Bioscience and Biotechnology Applied to Pharmacy, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stingray injuries represent a significant occupational hazard, particularly for fishermen, and are commonly caused by freshwater stingrays of the Potamotrygonidae family. These stingrays are equipped with a sharp, bilaterally serrated spine that delivers venom, inducing vasoconstriction, severe pain, and ischemia. Such injuries are not only intensely painful but also debilitating, often rendering victims unable to work for weeks or even months. Traditional self-treatment practices, including the application of urine and herbal remedies, are widely relied upon in affected communities but are scientifically unproven and frequently lead to delayed or suboptimal care. This study presents two clinical cases of freshwater stingray envenomation from Roraima, the northernmost state of Brazil located within the Amazon Rainforest. Both cases were managed at the infectious disease unit of the General Hospital in Boa Vista, the state capital. Patients received evidence-based medical care, including intravenous antibiotic therapy and surgical debridement to remove necrotic and devitalized tissue. In one case, advanced negative pressure wound therapy (NPWT) was utilized during dressing changes, resulting in a clean wound devoid of edema and necrotic tissue, demonstrating the technique's effectiveness in promoting wound healing. By accelerating wound healing and mitigating complications such as infections and chronic wounds, NPWT significantly enhance patient outcomes. Furthermore, this study underscores the limitations of traditional remedies and advocates for the adoption of evidence-based interventions, particularly in regions like the Brazilian Amazon, where access to healthcare can be challenging.

Indexed as

Amazonepidemiologyichthyismstingray accidentstingray management

Identifiers

PMID40130256
PMCPMC11931577

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.