Evidence map›Paper›PMID 40130219›Full record

ArticleJournal of arrhythmia2025

Risk stratification of elderly patients with Brugada syndrome: Results from a large Japanese cohort of idiopathic ventricular fibrillation.

Tetsuji Shinohara, Masahiko Takagi, Tsukasa Kamakura, Yuki Komatsu, Yoshiyasu Aizawa, Yukio Sekiguchi, Yasuhiro Yokoyama, Naohiko Aihara, Masayasu Hiraoka, Kazutaka Aonuma and 1 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tetsuji ShinoharaDepartment of Cardiology and Clinical Examination, Faculty of Medicine Oita University Oita Japan.ORCID https://orcid.org/0000-0002-6106-6017
Masahiko TakagiDepartment of Medicine II Kansai Medical University Moriguchi Japan.
Tsukasa KamakuraDivision of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine National Cerebral and Cardiovascular Center Osaka Japan.
Yuki KomatsuDepartment of Cardiology, Faculty of Medicine University of Tsukuba Tsukuba Japan.ORCID https://orcid.org/0000-0002-3413-765X
Yoshiyasu AizawaDepartment of Cardiovascular Medicine Nippon Medical School Tokyo Japan.
Yukio SekiguchiDepartment of Cardiovascular Internal Medicine Sakakibara Heart Institute Fuchu Japan.
Yasuhiro YokoyamaDivision of Cardiology, Department of Internal Medicine Daisan Kitashinagawa Hospital Tokyo Japan.
Naohiko AiharaDepartment of Internal Medicine Senri Central Hospital Suita Japan.
Masayasu HiraokaDepartment of Cardiology Tokyo Medical and Dental University Tokyo Japan.ORCID https://orcid.org/0000-0001-9533-6153
Kazutaka AonumaDepartment of Cardiology Saiseikai Mito Hospital Mito Japan.
Japan Idiopathic Ventricular Fibrillation Study (J‐IVFS) Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Brugada syndrome (BrS) is an inherited cardiac channelopathy associated with a high risk of sudden cardiac death (SCD) due to ventricular fibrillation (VF). Although implantable cardioverter-defibrillators (ICDs) are the primary therapy for SCD prevention, the risk stratification of elderly patients with BrS remains unclear. This study aimed to evaluate the incidence and risk factors of life-threatening arrhythmias in elderly patients with BrS. Methods: We analyzed 523 patients with BrS (mean age 51 ± 13 years, 497 men) enrolled in the multicenter prospective Japan Idiopathic Ventricular Fibrillation Study. Patients were categorized into the elderly (>60 years, Results: During a mean follow-up of 106 ± 62 months, 59 patients (11%) experienced CE. The annual CE incidence was lower in the elderly group than in the nonelderly group (0.7% vs. 1.5%, Conclusions: Elderly patients with BrS have a better prognosis than nonelderly patients, particularly if they are asymptomatic. A history of VF is a key risk factor for life-threatening arrhythmias in elderly patients with BrS.

Indexed as

Brugada syndromeelderlyprogrammed electrical stimulationrisk stratificationventricular fibrillation

Identifiers

PMID40130219
PMCPMC11931591

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