Evidence map›Paper›PMID 40130212›Full record

ArticleKidney medicine2025

Disentangling Dialysis Facility and Transplant Center Factors on Evaluation Start Following Referral for Kidney Transplantation: A Regional Study in the United States.

Laura McPherson, Laura C Plantinga, Penelope P Howards, Michael Kramer, Rachel E Patzer

Abstract read
In one paragraph

Article in Kidney medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura McPhersonDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Laura C PlantingaDivisions of Rheumatology and Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA.
Penelope P HowardsDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Michael KramerDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Rachel E PatzerDivision of Transplantation, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN.

Funding

Reducing Racial Disparities in Access to Kidney Transplantation: the RaDIANT Regional StudyU01MD010611 · NIMHD · EMORY UNIVERSITY · PI PATZER, RACHEL E · 2016 to 2020
$2.8M
Improving Quality and Access to Early Steps in Kidney TransplantationR01DK122701 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI PASTAN, STEPHEN, PATZER, RACHEL E · 2019 to 2022
$2.5M
Early Access to Kidney Transplantation among Patients with Lupus NephritisF31DK135379 · NIDDK · EMORY UNIVERSITY · PI MCPHERSON, LAURA · 2023 to 2024
$71k
NIDDK NIH HHS F31 DK135379NIDDK NIH HHS R01 DK122701NIMHD NIH HHS U01 MD010611
6 · The paper itself

Abstract

Rationale & Objective: Little is known about the relative importance of dialysis facilities and transplant centers on variability in starting an evaluation among patients referred for kidney transplant. The primary objective of this study was to leverage cross-classified multilevel modeling to simultaneously examine the contextual effects of dialysis facilities and transplant centers on variation in the start of the transplant evaluation process. Study Design: Retrospective cohort study. Setting & Participants: Dialysis patients referred for kidney transplant to transplant centers across the Southeast, Northeast, New York, or Ohio River Valley US regions from January 1, 2012, to December 31, 2020, were identified from the United States Renal Data System and the Early Steps to Transplant Access Registry and followed through June 30, 2021. A total of N=25,488 referred patients were nested with 1,720 dialysis facilities and 26 transplant centers. Outcomes: Starting an evaluation for kidney transplant at a transplant center within 6 months of referral. Analytical Approach: A series of multilevel models were performed to estimate the variability in starting an evaluation for kidney transplant within 6 months of referral. The between-dialysis facility and/or transplant center variation in starting an evaluation was quantified using the median OR. Results: Among 25,488 dialysis patients referred for kidney transplantation, 51% of patients started an evaluation at a transplant center within 6 months of referral. In multilevel models, the median OR between transplant centers was higher (indicating higher unexplained variability) than the dialysis facility median OR, regardless of measured patient, dialysis facility, and transplant center characteristics. Limitations: Early transplant access data was limited to 20 of 48 transplant centers across these 4 regions. Conclusions: When taking dialysis facilities and transplant centers into account, variation in starting an evaluation for kidney transplant appeared at both the dialysis facility and transplant center-level but was more apparent among transplant centers.

Indexed as

Dialysis facilitiesevaluation starthealth equitykidney transplantationtransplant centers

Identifiers

PMID40130212
PMCPMC11930794

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.