ArticleCureus2025
Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, and Somatic (VEXAS) Syndrome: A Diagnostic and Therapeutic Conundrum.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Vacuoles, E1 enzyme, X-linked, autoinflammatory, and somatic (VEXAS) syndrome is an adult-onset systemic autoinflammatory condition notable for being simultaneously an autoinflammatory syndrome and a hematologic disease. Here, we present a clinical case of a 67-year-old man referred to the Autoimmune Diseases Outpatient Clinic for a two-year history of maculopapular rash involving the face, trunk, back, and upper limbs. At the time, the patient had already undergone three skin biopsies, with conflicting results. His physical exam was only remarkable for multiple roundly shaped maculopapules involving the trunk, back, and extremities. Laboratory evaluation revealed elevated erythrocyte sedimentation rate and C-reactive protein, increased alpha-2 zone in the serum protein electrophoresis, and positive IgM antibodies against
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