Evidence map›Paper›PMID 40130122›Full record

ArticleCureus2025

Subcutaneous Lanreotide Depot: A Diagnostic Pitfall in Neuroendocrine Tumor Imaging.

Tsutomu Nishida

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tsutomu NishidaDepartment of Gastroenterology, Toyonaka Municipal Hospital, Toyonaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lanreotide depot, a long-acting somatostatin analog, improves progression-free survival in neuroendocrine tumor (NET) patients. However, persistent subcutaneous depots can appear as metastatic lesions on imaging, potentially leading to misdiagnosis. We report the case of a 70-year-old man with grade 2 NET (Ki-67: 5.9%) undergoing six years of lanreotide treatment. Follow-up imaging revealed stable primary disease. However, nodular lesions in the buttock were identified on the CT scan performed eight months after the start of treatment. A retrospective review of a CT scan taken two months after treatment initiation revealed that these nodules were already present and had gradually increased in number, allowing for their correct identification as persistent lanreotide depots. This case underscores the need for heightened diagnostic awareness to prevent unnecessary interventions and ensure accurate management.

Indexed as

computed tomographyct imaginglanreotideneuroendocrine tumoroctreoscansomatostatin analog

Identifiers

PMID40130122
PMCPMC11931402

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.