ArticleJournal of Taibah University Medical Sciences2025
Epidemiology of latent tuberculosis and associated risk factors in Al-Madinah, Saudi Arabia: A hospital-based cross-sectional study.
Article in Journal of Taibah University Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Prevalence of tuberculosis-related chest radiographic abnormalities among individuals with latent tuberculosis infection in Gulf Cooperation Council countries: A systematic review and meta-analysis.New microbes and new infections · 2026Review
- Cross-sectional analysis of tuberculosis burden and risk factors in Swabi district, Khyber Pakhtunkhwa, Pakistan.Tropical diseases, travel medicine and vaccines · 2025Article
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8 authors.
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Abstract
Objectives: To investigate the epidemiology of latent tuberculosis infection (LTBI) and associated risk factors among adults in Al-Madinah, KSA, and to identify vulnerable populations for targeted interventions. Methods: This hospital-based cross-sectional study was conducted at Prince Mohammed Bin Abdulaziz Hospital, Al-Madinah, from January 2021 to December 2022. Participants aged >14 years were screened for LTBI using the QuantiFERON®-TB Gold In-Tube test. People with active tuberculosis were excluded. Data on demographics, comorbidities, and risk factors were analyzed using multivariate logistic regression to identify factors associated with LTBI. Results: In total, 773 participants were included and 291 (37.6 %) tested positive for LTBI. Multivariate analysis identified greater age, male sex, diabetes mellitus, and connective tissue disorders as significant risk factors for LTBI. Non-Saudi nationality was associated with higher odds of LTBI (adjusted odds ratio [aOR], 3.86; 95 % confidence interval (95 % CI), 1.80-8.27), whereas the risk was lower for Saudi nationals (aOR, 0.34; 95 % CI, 0.25-0.47). Conclusions: This study highlights the burden of LTBI in Al-Madinah, and specific demographic and medical risk factors. These findings underscore the importance of personalized public health strategies and preventive measures for controlling LTBI progression in high-risk populations.
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