ArticleFrontiers in pharmacology2025
Sodium alginate hydrogel loaded with upconversion nanoparticles and magnesium ions enhances bone regeneration and photodynamic tumor therapy.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Experimental Models and Nanotechnology-Based Platforms in Oral Squamous Cell Carcinoma: From Tumor Biology to Translational Applications.Pharmaceutics · 2026Review
- Preparation Method of Upconversion Nanoparticles and Its Biological Application.Nanomaterials (Basel, Switzerland) · 2026Review
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9 authors.
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Abstract
Introduction: Oral squamous cell carcinoma (OSCC) usually invades the jawbone over the course of the disease. Hence, it is necessary to consider the treatment of the tumor and repair of the jawbone, and the treatment process is very complicated. However, conventional therapy for OSCC mainly emphasizes tumor removal, which often fails to address the repair of jawbone defects and destroys residual tumor cells after treatment. Methods: In this study, we designed a composite hydrogel platform (SUMg) of sodium alginate loaded upconversion nanoparticles (UCNP) and magnesium particles (MPs), in which UCNP was coated with folic acid and chlorin e6 to prepare UFC. The physicochemical and biological properties of the prepared SUMg, including swelling test, element mapping, cell behaviors, Results: Discussion: This work demonstrated the potential of SUMg in bone regeneration and inhibition of tumor growth, providing valuable insight for OSCC treatment.
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