ArticleFrontiers in pharmacology2025
Inhibition of carbohydrate digestive enzymes by a complementary essential oil blend: in silico and mixture design approaches.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Volatile Organic Compounds and Beyond: Chemical Diversity and Biological Activities ofMolecules (Basel, Switzerland) · 2026Review
- Multi-Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation.Food science & nutrition · 2026Article
- Synergistic and Additive Interactions in Essential Oils Obtained from Combined Plant Materials: Enhanced Control of Insect Pests.Molecules (Basel, Switzerland) · 2026Article
- Applications of Opuntia ficus-indica (L.) mill seed oil from eastern morocco including chemical profiling, antibacterial activity, and docking.Scientific reports · 2026Article
- Optimization of Eugenol, Camphor, and Terpineol Mixture Using Simplex-Centroid Design for Targeted Inhibition of Key Antidiabetic Enzymes.Current issues in molecular biology · 2025Article
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Authors and funding
13 authors.
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Abstract
Background: The increasing demand for natural alternatives in diabetes treatment has driven research into plant-derived metabolites, particularly essential oils (EOs) with bioactive properties. This study aims to optimize an EO mixture for inhibiting two key enzymes involved in glucose digestion: pancreatic α-amylase and intestinal α-glucosidase. Methods: Essential oils were extracted from three Moroccan medicinal plants: false yellowhead ( Results: GC-MS analysis identified 32 metabolites in Conclusion: These findings highlight the potential of optimized EO formulations as natural alternatives for managing hyperglycemia and developing novel diabetes therapies.
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