Evidence map›Paper›PMID 40129884›Full record

ReviewJournal of asthma and allergy2025

Notch Signaling Pathway Interfering as a Possible Asthma Treatment: A Narrative Review.

Jingya Wang, Kang Yan, Leilei Ma, Xianglei Yan, Zihan Meng, Ji-An Li, Meng Wang, Chenguang Du, Yueyue Yu

Abstract readReview
In one paragraph

Review in Journal of asthma and allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Multifaceted mechanistic exploration ofFrontiers in cell and developmental biology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jingya Wang *College of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.ORCID 0000-0002-0359-1016
Kang Yan *College of Traditional Chinese Medicine, Hebei University, Baoding, Hebei, People's Republic of China.ORCID 0000-0002-4238-7296
Leilei Ma *College of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.
Xianglei YanCollege of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.
Zihan MengCollege of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.ORCID 0009-0007-2825-6859
Ji-An LiCollege of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.
Meng WangCollege of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.
Chenguang DuCollege of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.
Yueyue YuCollege of Traditional Chinese Medicine, North China University of Technology, Tangshan, Hebei, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma is a respiratory disease common among all age groups, and there is currently no cure that can be applied, as the patients react differently to the available treatments. Recent studies have shown that the Notch signaling pathway can regulate the dynamic balance between Th1 and Th2 cells, inhibit airway inflammation, reduce airway hyperresponsiveness and remodeling, and promote mesenchymal stem cell (MSCs) homing. This study conducted a comprehensive search of multiple large databases and provided a narrative review of the role of the Notch signaling pathway in asthma.

Indexed as

bronchial asthmahyperresponsivenessinflammationnotch pathwayremodeling

Identifiers

PMID40129884
PMCPMC11932036

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.