Evidence map›Paper›PMID 40129880›Full record

ReviewToxicology reports2025

Zebrafish as a model for assessing biocide toxicity: A comprehensive review.

Ali Pourshaban-Shahrestani, Ali Rezazadeh, Jalal Hassan

Abstract readReview
In one paragraph

Review in Toxicology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ali Pourshaban-ShahrestaniDivision of Toxicology, Department of Comparative Bioscience, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Ali RezazadehDivision of Toxicology, Department of Comparative Bioscience, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Jalal HassanDivision of Toxicology, Department of Comparative Bioscience, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The utilization of biocides in a myriad of products has become a widespread and critical practice in recent years. Among these, quaternary ammonium compounds, polyhexamethylene, parabens, and triclosan are notably prevalent across various industrial applications. However, the incorporation of these biocides raises significant concerns regarding their toxicological profile. Not only do these chemicals pose potential risks to consumers using biocide-containing products, but their environmental discharge also represents a substantial threat to the biosphere. In our meticulous review, we examined approximately 150 articles from esteemed databases including PubMed, MDPI, and Google Scholar, ultimately utilizing at least 88 of these articles to inform our analysis. Our investigation encompassed studies that probe general toxicity, behavioral toxicity, cardiovascular toxicity, and genotoxicity, among other toxicological impacts. With this comprehensive approach, we explore the zebrafish (Danio rerio) as a prominent model organism in toxicology research. This review article aims to synthesize research employing zebrafish to evaluate biocide toxicity and ascertain the suitability of this model for comprehensive analysis of biocidal agents and their associated products.

Indexed as

BiocidesParabenPolyhexamethyleneQuaternary ammonium compoundTriclosanZebrafish

Identifiers

PMID40129880
PMCPMC11930722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.