ArticleRadiology case reports2025
Two case reports of ovarian clear cell carcinoma: Atypical MRI findings with a renal corticomedullary contrast-like appearance.
Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Two case reports of ovarian clear cell carcinoma with central necrosis representing a mille-feuille-like appearance on contrast-enhanced MRI.Radiology case reports · 2026Article
- MRI-based morphology of ovarian clear cell carcinomas.Abdominal radiology (New York) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The MR images of the two cases of ovarian clear cell carcinomas (CCCs), presenting as entirely solid-masses, revealed a band-like peripheral area and a geographic central area: The peripheral area images resembled those of the renal cortex, while the central area images resembled those of the renal medulla. Compared to the iliac muscle, the band-like peripheral area appeared iso-hyperintense on T2-weighted imaging (T2WI), isointense on unenhanced T1-weighted imaging (T1WI), hyperintense on diffusion-weighted imaging (DWI), and hypo-isointense on an apparent diffusion coefficient (ADC) map, with gradual enhancement on dynamic contrast-enhanced T1WI. The geographic central area of the tumor appeared hyperintense on T2WI, hypointense on T1WI, hypointense on DWI, and hyperintense on an ADC map, with less enhancement on dynamic contrast-enhanced T1WI. Simple total hysterectomy, salpingo-oophorectomy, and partial omentectomy were performed in both cases. Both tumors were entirely solid, and histopathological analysis revealed cancer cell proliferation accompanied by an increase in stromal fibrous tissue in the peripheral area. Edematous stroma and fibrosis were predominantly observed with minimal cancer cells in the central area. The patients were diagnosed with ovarian CCC (pT1a). The mechanism behind the appearance of peripheral and central areas with renal corticomedullary contrast in such cases remains unknown, and MRI can provide valuable insights for the differential diagnosis of epithelial ovarian cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.