Evidence map›Paper›PMID 40129758›Full record

ArticleIDCases2025

Hemophagocytic lymphohistiocytosis in a neonate with enterovirus infection: Case report and literature review.

Hua Hu, Shukun Yu, Jing Zhang, Hongping Zhang

Abstract readCase Reports
In one paragraph

Article in IDCases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hua HuDepartment of Health Management and Clinical Medicine, Wuhan Polytechnic University, Wuhan, Hubei 430023, China.
Shukun YuWuhan Dongxihu District Centers for Disease Control and Prevention, Dongxihu District, Wuhan, Hubei 430040, China.
Jing ZhangDepartment of Health Management and Clinical Medicine, Wuhan Polytechnic University, Wuhan, Hubei 430023, China.
Hongping ZhangDepartment of Health Management and Clinical Medicine, Wuhan Polytechnic University, Wuhan, Hubei 430023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses are the most common organisms causing hemophagocytic lymphohistiocytosis (HLH), and enterovirus infection is the most frequently diagnosed virus infection in the newborn period. However, in recent years, there have been relatively few reports of enterovirus infection in Chinese neonates complicated by HLH. Here, we describe a female preterm infant who contracted echovirus 11 at day 4 and rapidly developed sepsis during the following three days, along with fever, lethargy, disseminated intravascular coagulation (DIC), and sepsis. She was ultimately identified as having echovirus 11 complicated by HLH. This report will contribute to increasing public awareness of the link between HLH and echo 11 infection, which can aid in early identification and treatment.

Indexed as

EchovirusHemophagocytic lymphohistiocytosisInfectionNeonatePreterm

Identifiers

PMID40129758
PMCPMC11932653

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.