Evidence map›Paper›PMID 40129692›Full record

ArticleJournal of virus eradication2025

Genetic characterization on the nucleoprotein and fusion gene of wild-type measles virus circulating in Shanghai, 2001-2022.

Yunyi Li, Xiaoxian Cui, Ai Lin, Wei Tang, Yuying Yang, Wanju Zhang, Jiayu Hu, Zhi Li, Yanqiu Zhou

Abstract read
In one paragraph

Article in Journal of virus eradication, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yunyi LiInstitute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Xiaoxian CuiInstitute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Ai LinInstitute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Wei TangInstitute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Yuying YangInstitute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Wanju ZhangInstitute of Microbiology Laboratory, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Jiayu HuEPI Department, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Zhi LiEPI Department, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, 201106, China.
Yanqiu ZhouInstitute of Microbiology Laboratory, Shanghai Institute of Preventive Medicine, Shanghai, 201106, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measles is an acute and highly contagious viral disease that poses significant public health challenges globally. Since 2001, continuous virologic surveillance has been conducted in Shanghai, enabling a comprehensive analysis of the evolution of the nucleoprotein (N gene) and fusion gene (F gene) of the measles virus (MeV) over a 21-year period. Between 2001 and 2022, there were a total of 1405 MeV strains isolated by the Shanghai Center for Disease Control and prevention (SCDC), including 6 strains of genotype D8, 8 strains of genotype B3, 12 strains of genotype H1b, and the remaining strains of genotype H1a. Reverse transcription polymerase chain reaction (RT-PCR) was used to amplify the 3' end of the N gene (450 nt) and the complete sequence of the F gene (1622 nt) from the viral isolates. Sequencing of the RT-PCR products was followed by nucleotide and amino acid phylogenetic analyses. The substitution rates were for the F and N genes in Shanghai were determined to be 0.89 × 10

Indexed as

Fusion proteinGenotypingMeaslesMeasles vaccineShanghai-191Viral surveillance

Identifiers

PMID40129692
PMCPMC11930667

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.