ArticlePatient preference and adherence2025
The Relationship Between Intolerance of Uncertainty and Treatment Adherence: The Moderating Effect of Self-Compassion on the Chain Mediation Model.
Article in Patient preference and adherence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Intolerance of uncertainty and attitudes toward cancer as predictors of spiritual well-being in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The low follow-up compliance of young and middle-aged patients with newly diagnosed pulmonary nodules warrants attention, primarily due to a series of factors such as occupational, familial, and social pressures. Enhancing follow-up adherence is essential for preventing pulmonary nodule progression and reducing lung cancer mortality. Existing research indicates that intolerance of uncertainty is closely associated with patients' follow-up compliance; however, further in-depth investigation into its influencing mechanisms and potential improvement strategies is required. Patients and Methods: This study conducted a questionnaire survey among 319 young and middle-aged patients newly diagnosed with pulmonary nodules, examining the moderating effect of self-compassion on follow-up compliance and investigating the chain intermediary role of negative interpretation bias and trust in linking intolerance of uncertainty to follow-up compliance. Results: The study found that women, urban residents, and patients over 50 years old demonstrated relatively higher follow-up compliance. Intolerance of uncertainty was found to negatively predict follow-up compliance and indirectly influenced patients' follow-up behavior through the mediating effects of negative interpretation bias and trust. Furthermore, self-compassion significantly moderated the relationship between trust and follow-up compliance. Conclusion: The findings provide a solid theoretical foundation for developing multidimensional interventions targeting both protective and risk factors. Specifically, mitigating the impact of intolerance of uncertainty on follow-up compliance can improve long-term patient health outcomes. The novel application of the chain mediation model provides valuable insights for future research and clinical practice, particularly in enhancing patient engagement and adherence to follow-up care. Future longitudinal studies are needed to explore additional influencing factors and validate these findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.