ArticleResearch and practice in thrombosis and haemostasis2025
Fibrinogen levels and bleeding risk in adult extracorporeal cardiopulmonary resuscitation: multicenter observational study subanalysis.
Article in Research and practice in thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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10 authors.
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Abstract
•Hypofibrinogenemia frequently occurs in extracorporeal cardiopulmonary resuscitation (ECPR) and may heighten bleeding risk. This subanalysis of a multicenter observational study (SAVE-J II) included 2,100 adult patients receiving ECPR after out-of-hospital cardiac arrest at 36 facilities in Japan.•Overall, 7.5% of patients experienced non-cannulation hemorrhagic complications, and those with fibrinogen levels below 140 mg/dL at ECPR initiation faced significantly higher bleeding risk. These findings underscore the importance of monitoring and managing fibrinogen levels in ECPR to mitigate hemorrhagic events and improve patient outcomes.
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