Evidence map›Paper›PMID 40129540›Full record

ArticleERJ open research2025

Randomised trial of assessing diagnostic yield in transbronchial biopsy with a guide sheath.

Hao-Chun Chang, Yao-Wen Kuo, Ching-Kai Lin, Lih-Chyun Chang, You-Yi Chen, Ching-Yao Yang, Jung-Yien Chien, Chia-Lin Hsu, Tzu-Hsiu Tsai, Chao-Chi Ho and 2 more

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Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hao-Chun ChangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hsinchu Branch, Biomedical Park Hospital, Hsinchu County, Taiwan.ORCID https://orcid.org/0000-0002-1236-5600
Yao-Wen KuoDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
Ching-Kai LinDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Cancer Center, Taipei City, Taiwan.
Lih-Chyun ChangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
You-Yi ChenDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Yunlin Branch, Yunlin County, Taiwan.
Ching-Yao YangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
Jung-Yien ChienDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.ORCID https://orcid.org/0000-0002-7718-0594
Chia-Lin HsuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
Tzu-Hsiu TsaiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
Chao-Chi HoDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
Jin-Yuan ShihDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei City, Taiwan.
Chong-Jen YuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Taiwan University Hsinchu Branch, Biomedical Park Hospital, Hsinchu County, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Radial probe endobronchial ultrasound (rEBUS)-guided transbronchial biopsy (TBB) with a guide sheath (GS) is widely used to diagnose peripheral lung lesions (PPLs), but there is no consensus on whether it increases the diagnostic yield. We conducted this prospective study to compare the diagnostic yield of the GS method to the conventional method without a GS. Methods: From November 2019 to March 2023, patients with PPLs were recruited and randomly assigned to rEBUS-TBB with a GS (GS group) or without a GS (conventional group). The histopathology, cytology and microbiology yield rates, as well as procedure time and post-procedure adverse events, of the two groups were compared. Results: A total of 102 patients were enrolled (54 in the GS group and 48 in the conventional group). The pathology yield showed no statistical difference between the two groups (75.9% Conclusion: The pathology yield of rEBUS TBB with a GS did not significantly differ from the conventional method. However, a GS could improve the cytology yield rate and reduce the risk of bleeding. To enhance the microbiology yield, additional bronchial washing should be utilised.

Identifiers

PMID40129540
PMCPMC11931523

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.