Evidence map›Paper›PMID 40129510›Full record

ArticleHealth science reports2025

Can External Neuromodulation Garments Improve Gait and Function in Children With Cerebral Palsy? A Prospective Single-Arm Study.

Lindsey Jean Ross Weller, Shelly-Anne Marie Sherwood, Shin Huey Ng, Maheswari Vellaichamy, Asila Alia Noordin, Ling Ying Tan, Arjandas Mahadev, Tong Hong Yeo, Zhi Min Ng

Registry-linked trialAbstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07202195 (Home-Based Neuromodulation Suits for Reducing Spasticity and Ataxia in Multiple Sclerosis), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07202195 narecruitingnot on this mapstarted 2026, after this paper: background citation

Home-Based Neuromodulation Suits for Reducing Spasticity and Ataxia in Multiple Sclerosis: A Multi-center RCT

TypeinterventionalSponsorDaphne KosRan2026 to 2027Enrolled70ConditionsMultiple Sclerosis, MS (Multiple Sclerosis), Spasticity With Multiple Sclerosis, Ataxia - OtherArmselectro-stimulation suit, Usual Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lindsey Jean Ross WellerPhysiotherapy Department KKH Women's and Children's Hospital Singapore Singapore.ORCID 0000-0002-7091-724X
Shelly-Anne Marie SherwoodPhysiotherapy Department KKH Women's and Children's Hospital Singapore Singapore.
Shin Huey NgPhysiotherapy Department KKH Women's and Children's Hospital Singapore Singapore.
Maheswari VellaichamyPhysiotherapy Department KKH Women's and Children's Hospital Singapore Singapore.
Asila Alia NoordinPhysiotherapy Department KKH Women's and Children's Hospital Singapore Singapore.
Ling Ying TanDivision of Nursing KKH Women's and Children's Hospital Singapore Singapore.
Arjandas MahadevPaediatric Orthopaedic Surgery KKH Women's and Children's Hospital Singapore Singapore.
Tong Hong YeoNeurology Service, Paediatric Medicine KKH Women's and Children's Hospital Singapore Singapore.
Zhi Min NgNeurology Service, Paediatric Medicine KKH Women's and Children's Hospital Singapore Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The Exopulse Mollii Suit is an external electrical stimulation garment that is designed to reduce spasticity through electrical stimulation of targeted muscles. Our aims were to study the impact of the garment in improving gait and function in children with cerebral palsy (CP). Methods: Individuals aged 4-18 years with spastic CP, Gross Motor Function Classification System level I-III were included for a prospective single-arm study from January 2021 to January 2022. Participants wore the suit for 4 weeks 60 min a day. Outcome measures taken pre, post and 1-month-post intervention included: 3D gait analysis (gait profile score, gait deviation index and temporo-spatial parameters), gross motor function measure-88 (GMFM-88), EQ-5D-Y, compliance rate, adverse event and satisfaction. Paired Results: Twenty children (median age 7 [range: 4-16; interquartile range: 3.1] years, 55% female, 45% male were recruited. Post-intervention results showed there was no improvement in the gait profile but there was an improving trend in temporo-spatial parameters GMFM Domain C Conclusion: The positive changes in gait profile and function were no longer significant at 1-month post-intervention. Further studies with a longer intervention period and concurrent strengthening program are required. Implications for Physiotherapy Practice: Using the Molli Suit for 60 min a day for 4 weeks, may be useful in improving:(1) Gait cadence in children with CP. (2) Gross motor function in terms of crawling and kneeling in children with CP.

Indexed as

cerebral palsyelectrical stimulationspasticity

Identifiers

PMID40129510
PMCPMC11930893

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.