Evidence map›Paper›PMID 40129260›Full record

Trial reportPhysiological reports2025

Changes in plasma cytokines following a 60-h fast are not influenced by the addition of exercise despite elevated ketones in healthy young adults.

Tori Bouck, Justin Monteleone, Jennifer Duffy, Philip N Ainslie, Jonathan P Little, Kate N Thomas, Travis D Gibbons, Hashim Islam

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tori BouckSchool of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Justin MonteleoneSchool of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Jennifer DuffySchool of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Philip N AinslieSchool of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.
Jonathan P LittleSchool of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.ORCID 0000-0002-9796-2008
Kate N ThomasDepartment of Surgical Sciences, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
Travis D GibbonsDepartment of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, USA.
Hashim IslamSchool of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.ORCID 0000-0002-7145-0522

Funding

Killam TrustsPostdoctoral fellowshipMichael Smith Health Research BC RT-2021-1529
6 · The paper itself

Abstract

Immunometabolic processes maintain physiological homeostasis and are implicated in various chronic diseases. Fasting and exercise independently alter metabolic and immunological processes; their combination could provide insights into immunometabolic interactions. Using a randomized crossover design, 15 healthy adults (six females, nine males, 26.5 ± 4.3 years) fasted for 60 h with and without the addition of a 3 h cycling bout (65%-80% VO

Indexed as

CytokinesExerciseFastingKetones3-Hydroxybutyric AcidAdultBlood GlucoseCross-Over StudiesFemaleHumansInsulinMaleYoung Adult3-Hydroxybutyric AcidBlood GlucoseCytokinesInsulinKetonesimmunometabolisminflammationinterleukin‐10interleukin‐6leukocytestumor necrosis factor‐alpha

Identifiers

PMID40129260
PMCPMC11933719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.