Evidence map›Paper›PMID 40129126›Full record

ArticleThoracic cancer2025

One-Stage Bilateral Pulmonary Nodule Resection via Unilateral Thoracic Cavity Access: A Single-Center Experience of 12 Cases.

Zhen Wang, Zhaolei You, Yingjian Song, Hua Ji, Guodong Jiang, Xiaokun Bu, Jingyu Zhang, Tengfei Yi, Jian Fang, Xiaofeng Yu

Abstract read
In one paragraph

Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhen WangDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.ORCID https://orcid.org/0000-0003-3710-8640
Zhaolei YouDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.ORCID https://orcid.org/0009-0002-8827-0410
Yingjian SongDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Hua JiDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Guodong JiangDepartment of Cardiothoracic Surgery, The People's Hospital of Zhaoyuan City, Yantai, People's Republic of China.
Xiaokun BuDepartment of Cardiothoracic Surgery, Yantai Yeda Hospital, Yantai, People's Republic of China.
Jingyu ZhangDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Tengfei YiDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Jian FangDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.ORCID https://orcid.org/0009-0009-6646-5875
Xiaofeng YuDepartment of Thoracic Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.ORCID https://orcid.org/0009-0006-8038-2062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical intervention remains the primary therapeutic modality for managing multiple pulmonary nodules. However, in cases with bilateral pulmonary nodules, one-stage bilateral resection is discouraged due to tumor aggressiveness and surgical invasiveness. In light of this, we investigated an innovative approach, termed one-stage bilateral pulmonary nodule resection via unilateral thoracic cavity access.

methodsFrom July 2022 to September 2024, a cohort of 12 patients with bilateral pulmonary nodules were enrolled in this study. This technique involves initial unilateral transcostal incision for segmental or lobectomy of a nodule on one side, followed by bilateral mediastinal pleura incision through the anterior mediastinum, facilitating subsequent wedge resection of the contralateral nodule. Clinical and pathological data, along with perioperative imaging findings and follow-up information, were systematically collected and subjected to a comprehensive retrospective analysis.

resultsA total of 25 nodules were resected from 12 patients. Regarding surgical approaches, nine patients underwent right thoracic incision, while three patients underwent left thoracic incision. Intraoperatively, seven patients received bilateral wedge resections, whereas five patients underwent segmentectomy on one side combined with wedge resection on the contralateral side. R0 resection of the contralateral nodules was successfully achieved during the procedures. The average distance between the surgical margin and the contralateral nodules was 12.5 mm, ranging from 5 mm to 25 mm. Of the 12 patients, one (Patient 6) was lost to follow-up, while the remaining 11 patients underwent postoperative chest CT examinations. The median follow-up duration for these 11 patients was 105 days (range: 36-857 days). No evidence of bilateral pleural effusion or tumor recurrence was detected on follow-up chest CT scans.

conclusionsThis study offers the potential to concurrently address bilateral pulmonary nodules, thereby sparing patients from the need for a subsequent hospitalization for surgical intervention.

Indexed as

Lung NeoplasmsMultiple Pulmonary NodulesPneumonectomyThoracic CavityAdultAgedFemaleHumansMaleMiddle AgedRetrospective Studiesbilateral pulmonary nodulesone‐stage resectionunilateral transcostal incision

Identifiers

PMID40129126
PMCPMC11933441

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.