Evidence map›Paper›PMID 40128992›Full record

ArticleInternal medicine (Tokyo, Japan)2025

A Serial Assessment of T1 and T2 Mapping Cardiac Magnetic Resonance before and after Heart Failure Onset in a Case of Cardiomyopathy in Anti-mitochondrial Antibody-positive Myositis.

Mitsuru Ishizuka, Hideaki Suzuki, Satoshi Higuchi, Hidenobu Takagi, Naoki Suzuki, Rumiko Izumi, Hirofumi Watanabe, Haruka Sato, Taijyu Satoh, Saori Miyamichi-Yamamoto and 10 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Mitsuru IshizukaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Hideaki SuzukiDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Satoshi HiguchiDepartment of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Japan.
Hidenobu TakagiDepartment of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Japan.
Naoki SuzukiDepartment of Neurology, Tohoku University Graduate School of Medicine, Japan.
Rumiko IzumiDepartment of Neurology, Tohoku University Graduate School of Medicine, Japan.
Hirofumi WatanabeDepartment of Pathology, Tohoku University Hospital, Japan.
Haruka SatoDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Taijyu SatohDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Saori Miyamichi-YamamotoDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Nobuhiro YaoitaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Kouki TakeuchiDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Marina AraiDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Hideka HayashiDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Kotaro NochiokaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Hiroyuki TakahamaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Shunsuke TatebeDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.
Hiroshi FujiiDepartment of Clinical Immunology and Rheumatology, Tohoku University Graduate School of Medicine, Japan.
Masashi AokiDepartment of Neurology, Tohoku University Graduate School of Medicine, Japan.
Satoshi YasudaDepartment of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 69-year-old woman presented with heart failure and progressive muscle weakness and was diagnosed as anti-mitochondrial antibody (AMA) myositis with cardiac involvement. Immunosuppressive therapy with prednisolone and intravenous cyclophosphamide significantly improved the symptoms, hemodynamics, and cardiac function. Cardiac magnetic resonance (CMR) T1 and T2 mapping showed elevated native T1, T2, and extracellular volume fractions during heart failure exacerbation (day 37) compared to pre-hospitalization values (10 months before admission) and follow-up conducted 6 and 12 months after admission. This case underscores the importance of comprehensive evaluation, such as serial CMR imaging and immunosuppressive therapy, in managing myocardial involvement in AMA-positive myositis.

Indexed as

AutoantibodiesCardiomyopathiesHeart FailureMagnetic Resonance ImagingMyositisAgedFemaleHumansImmunosuppressive AgentsPrednisoloneAutoantibodiesImmunosuppressive AgentsPrednisoloneanti-mitochondrial antibodycardiac magnetic resonancecardiomyopathymyocarditisT1 mappingT2 mapping

Identifiers

PMID40128992
PMCPMC12549050

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.