Investigation of the Number of Oral Bacteria in Patients with Chronic Obstructive Pulmonary Disease, Asthma, and Asthma and Chronic Obstructive Pulmonary Disease Overlap.

Toshiya Inui, Maya Tsuchiya, Takayasu Watanabe, Mitsuru Sada, Atsuto Mouri, Shinkichi Iwanari, Mitsuhiro Kamimura

Abstract read

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Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Authors and funding

7 authors.

Toshiya InuiPulmonology Department, National Hospital Organization Disaster Medical Center, Japan.

Maya TsuchiyaPulmonology Department, National Hospital Organization Disaster Medical Center, Japan.

Takayasu WatanabePulmonology Department, National Hospital Organization Disaster Medical Center, Japan.

Mitsuru SadaPulmonology Department, National Hospital Organization Disaster Medical Center, Japan.

Atsuto MouriPulmonology Department, National Hospital Organization Disaster Medical Center, Japan.

Shinkichi IwanariDepartment of Oral and Maxillofacial Surgery, National Hospital Organization Disaster Medical Center, Japan.

Mitsuhiro KamimuraPulmonology Department, National Hospital Organization Disaster Medical Center, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Bacteria in the airways are reportedly involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) and asthma. In addition, oral bacteria are thought to contribute to respiratory diseases by migrating to the airway. Therefore, we investigated whether or not the number of oral bacteria influences COPD, asthma, and asthma and COPD overlap (ACO). Methods We analyzed the correlations between the number of oral bacteria and clinical variables, such as pulmonary function tests, in patients with COPD, asthma, and ACO whose condition was stable and who visited our center from August 2019 to December 2020. The number of oral bacteria was assessed using the dielectrophoretic impedance measurement method. Results In patients with COPD (n=50), the number of oral bacteria was significantly negatively correlated with the percentage predicted forced expiratory volume in one second (%FEV

Indexed as

AsthmaAsthma-Chronic Obstructive Pulmonary Disease Overlap SyndromeBacteriaMouthPulmonary Disease, Chronic ObstructiveAgedFemaleForced Expiratory VolumeHumansMaleMiddle AgedRespiratory Function Testsairway inflammationasthmaasthma and COPD overlap (ACO)chronic obstructive pulmonary disease (COPD)oral bacteriarespiratory function test

Identifiers

PMID40128989

DOI10.2169/internalmedicine.4825-24

PMCPMC12549041

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.