Trial reportBMC medicine2025
Distal radial access to prevent radial artery occlusion for STEMI patients (RAPID III): a randomized controlled trial.
Trial report in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05461781 (Distal Radial Access for Primary Percutaneous Coronary Intervention in STEMI Patients to Prevent Acute Radial Artery Occlusion), which is not on this map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Distal Radial Access for Primary Percutaneous Coronary Intervention in STEMI Patients to Prevent Acute Radial Artery Occlusion
Who cites it
7 citing papers in PubMed.
- Distal versus proximal transradial access and radial artery occlusion: a meta-analysis and trial sequential analysis.Journal of thrombosis and thrombolysis · 2026Review
- Trans-radial and "Snuffbox" Access Versus Trans-femoral Access in Emergency Embolization: A Retrospective Comparative Analysis of 421 Procedures.Cardiovascular and interventional radiology · 2026Article
- Distal radial access in acute coronary syndrome patients with good arterial pulsation: a subgroup analysis from the KODRA registry.The Korean journal of internal medicine · 2026Observational
- Optimizing distal radial access: clinical and anatomical predictors of failure from the multicenter DISTAL registry.Coronary artery disease · 2026Article
- Percutaneous Coronary Intervention and vascular access complications: A contemporary review.NPJ cardiovascular health · 2026Review
- Distal radial access in interventional cardiology: technique, pitfalls and recommendations.Cardiovascular diagnosis and therapy · 2025Review
- The safety and efficacy of non-emergent percutaneous coronary intervention via distal radial artery access in patients with acute coronary syndrome.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCompared with conventional transradial access (TRA), distal radial access (DRA) is rarely used for percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI) and may be beneficial to prevent radial artery occlusion (RAO). We aimed to evaluate the incidence of RAO between DRA and TRA 24 h after primary PCI in patients with STEMI.
methodsThis is a single-center, open-label, prospective, randomized controlled trial conducted at Beijing Luhe Hospital, China, between January 2022 and July 2023. Five hundred and twenty patients (mean age: 61.3 ± 13.0 years; 81% male) with STEMI were randomly assigned to the DRA (n = 260) or TRA (n = 260) group. Primary PCI was performed using the radial artery access assigned study group. The primary endpoint was the rate of RAO assessed using Doppler ultrasound 24 h after primary PCI. Secondary outcomes included time taken for sheath insertion, access success rate, hemostasis time, fluoroscopy time, radiation dosage, and access-related complications.
resultsThe incidence of RAO was significantly lower in the DRA group than that in the TRA group (1.9% vs. 8.5%, P = 0.001). Access was successful in 94.6% of patients, and the crossover rate was 5.4% in both groups. The median time taken for sheath insertion was significantly longer (133 s vs. 114 s, P = 0.009), whereas the mean hemostasis time was shorter (209 ± 71 min vs. 372 ± 70 min, P < 0.001) in the DRA group. The incidence of modified Early Discharge After Transradial Stenting of Coronary Arteries (mEASY) ≥ II hematoma was lower in the DRA group (0.8% vs. 3.5%, P = 0.033). However, there was no significant difference in fluoroscopy time, radiation dosage, or access-related complications.
conclusionsIn patients with STEMI undergoing primary PCI, compared with TRA, DRA prevented RAO 24 h postoperatively and was associated with shorter hemostasis time and a lower incidence of mEASY ≥ II hematoma.
trial registrationClinical Trials.gov Identifier: NCT05461781.
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