Evidence map›Paper›PMID 40128780›Full record

ArticleJournal of orthopaedic surgery and research2025

Deformity angular distance ratio independently predicts intraoperative neuromonitoring alerts in spinal deformity correction.

Jiajun Ni, Xinhu Guo, Zhuoran Sun, Chunwei Zhao, Zhongqiang Chen, Yan Zeng

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Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Predictive value of deformity angular ratio (DAR) for intraoperative neuromonitoring (IONM) signal loss and neurological complications in spinal deformity surgery: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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5 · Who and what money

Authors and funding

6 authors.

Jiajun NiDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China.
Xinhu GuoDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China.
Zhuoran SunDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China.
Chunwei ZhaoDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China.
Zhongqiang ChenDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China.
Yan ZengDepartment of Orthopedics, Peking University Third Hospital, Beijing, 100191, China. zy7311@sohu.com.

Funding

The National Natural Science Foundation of China 82272540
6 · The paper itself

Abstract

backgroundIntraoperative neuromonitoring (IONM) alerts are critical concerns for surgeons performing spinal deformity corrective surgeries, as they indicate a heighteded risk of postoperative neurological deficits. Previous studies have demonstrated that patients with large Cobb angle or elevated deformity angular ratio (DAR) are at an increased risk of IONM alerts. However, spinal curves with similar Cobb angles and DARs may exhibit significantly different risks of IONM alerts during surgery. Current methods for evaluating spinal deformity fail to comprehensively and accurately reflect its severity. The purpose of this study was to investigate whether the deformity angular distance ratio (DADR) serves as an independent predictor of IONM alerts during corrective surgery for spinal deformity.

methodsThis study analyzed a consecutive series of 404 patients undergoing corrective surgery at a single academic center. Preoperative radiographs were used to calculate the DAR and DADR. Twelve clinically relevant candidate variables were selected for univariable analysis. Multivariable logistic regression analysis was then conducted to identify independent predictors of IONM alerts.

resultsThe incidence of IONM alerts in this cohort was 25.2%. Univariable analysis identified several factors potentially associated with IONM alerts, including older age, type-III spinal cord morphology, location of apex, etiological diagnosis, preoperative sagittal Cobb angle, sagittal DAR, sagittal DADR, coronal DADR, total DAR, total DADR, three-column osteotomy, and preoperative neurological deficits. Multivariable analysis revealed that an apex location at C7-T4, preoperative neurological deficits, sagittal DADR, and total DADR were independent predictors of IONM alerts.

conclusionsAmong patients undergoing corrective surgeries for spinal deformities, the DADR is a robust measure of spinal deformity severity and is strongly correlated with the risk of IONM alerts. Compared to other deformity parameters, DADR is an independent predictor of IONM alerts. Additional independent predictors include the location of the apex and the presence of preoperative neurological deficits.

Indexed as

Intraoperative Neurophysiological MonitoringMonitoring, IntraoperativeScoliosisSpinal CurvaturesAdolescentAdultAgedChildCohort StudiesFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesYoung AdultCorrective surgeryDeformity angular distance ratioIntraoperative neuromonitoring alertNeurological deficitsSpinal deformity

Identifiers

PMID40128780
PMCPMC11931815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.